Precursor Forms of Vitamin D Reduce HIV-1 Infection In Vitro

BACKGROUND:Although the anti-HIV-1 effects of vitamin D (VitD) have been reported, mechanisms behind such protection remain largely unexplored. METHODS:The effects of two precursor forms (cholecalciferol/calciol at 0.01, 1 and 100 nM and calcidiol at 100 and 250 nM) on HIV-1 infection, immune activa...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2016-12, Vol.73 (5), p.497-506
Hauptverfasser:	Aguilar-Jimenez, Wbeimar, Villegas-Ospina, Simon, Gonzalez, Sandra, Zapata, Wildeman, Saulle, Irma, Garziano, Micaela, Biasin, Mara, Clerici, Mario, Rugeles, Maria T
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase 1 - analysis AIDS/HIV Anti-HIV Agents - pharmacology Calcifediol - pharmacology Cells Cells, Cultured Cholecalciferol - pharmacology Colombia Enzyme-Linked Immunosorbent Assay Flow Cytometry Gene expression Gene Expression Profiling Genotype & phenotype HIV Core Protein p24 - analysis HIV-1 - drug effects HIV-1 - growth & development HLA-DR Antigens - analysis Humans Immunity, Innate - drug effects Immunologic Factors - pharmacology Italy Lentivirus Leukocytes, Mononuclear - chemistry Leukocytes, Mononuclear - virology Membrane Glycoproteins - analysis Polymerase chain reaction Real-Time Polymerase Chain Reaction Retroviridae Vitamin D
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