Framingham risk score and severity of coronary artery disease

Objectives Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Easy-to-perform and reliable parameters are needed to predict the presence and severity of CAD and to implement efficient diagnostic and therapeutic modalities. We aimed to examine whether the Framingham risk scoring system can be used for this purpose. Methods A total of 222 patients (96 women, 126 men; mean age, 59.1 ± 11.9 years) who underwent coronary angiography were enrolled in the study. Presence of > %50 stenosis in a coronary artery was assessed as critical CAD. The Framingham risk score (FRS) was calculated for each patient. CAD severity was assessed by the Gensini score. The relationship between the FRS and the Gensini score was analyzed by correlation and regression analyses. Results The mean Gensini score was 18.9 ± 25.8, the median Gensini score was 7.5 (0–172), the mean FRS was 7.7 ± 4.2, and the median FRS was 7 (0–21). Correlation analysis revealed a significant relationship between FRS and Gensini score (r = 0.432, p