Light-emitting diodes downregulate cathelicidin, kallikrein and toll-like receptor 2 expressions in keratinocytes and rosacea-like mouse skin

Cathelicidin (LL‐37), Toll‐like receptor 2 (TLR‐2) and kallikreins (KLKs) are key inflammatory mediators in rosacea. Laser or light‐based devices have been successfully used for rosacea. We investigated the effects of light‐emitting diodes (LEDs) on LL‐37, KLKs, TLR‐2 and protease activity in cultur...

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Veröffentlicht in:	Experimental dermatology 2016-12, Vol.25 (12), p.956-961
Hauptverfasser:	Lee, Jee-Bum, Bae, Soo Hyeon, Moon, Ki Rang, Na, Eui Young, Yun, Sook Jung, Lee, Seung-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimicrobial Cationic Peptides - metabolism cathelicidin Cells, Cultured Humans Interleukin-8 - metabolism kallikrein Kallikreins - metabolism Keratinocytes - metabolism Keratinocytes - radiation effects light-emitting diode Mice, Inbred BALB C Receptor, PAR-2 - metabolism Receptors, Calcitriol - metabolism rosacea Rosacea - metabolism Rosacea - radiotherapy Toll-Like Receptor 2 - metabolism
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