Genotoxic effects of ochratoxin A in human-derived hepatoma (HepG2) cells

Ochratoxin A (OTA) is a widespread mycotoxin that occurs in many commodities from grains to coffee beans all over the world. Evidence is accumulating that OTA may cause cancer in humans. The compound was tested in micronucleus (MN) and single-cell gel electrophoresis (SCGE) assays in human-derived h...

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Veröffentlicht in:	Food and chemical toxicology 2002-08, Vol.40 (8), p.1085-1090
Hauptverfasser:	Ehrlich, V, Darroudi, F, Uhl, M, Steinkellner, H, Gann, M, Majer, B.J, Eisenbauer, M, Knasmüller, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Ames test Biological and medical sciences Carcinogens - toxicity Carcinoma, Hepatocellular Cell Division - drug effects Comet Assay Dose-Response Relationship, Drug HepG2 HepG2-S9 Humans Liver Neoplasms Medical sciences Micronouclei Micronucleus Tests Ochratoxin A Ochratoxins - toxicity Plant poisons toxicology Salmonella - drug effects Toxicology Tumor Cells, Cultured
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