Use of FTIR spectroscopy and PCA-LDC analysis to identify cancerous lesions within the human colon

•FTIR is a sensitive distribution indicator for the main biochemical compounds of healthy and cancerous colon tissue.•Cancerogenesis caused changes in spectrum representing the vibration of nucleic acids, protein and lipid functional groups.•Post-chemotherapy colon tissues FTIR spectrum was similar...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2017-02, Vol.134, p.259-268
Hauptverfasser:	Kaznowska, E., Depciuch, J., Szmuc, K., Cebulski, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - chemistry Adenocarcinoma - pathology Chemotherapy Colonic Neoplasms - chemistry Colonic Neoplasms - pathology Colorectal cancer Discriminant Analysis FTIR Humans PCA-LDC Principal Component Analysis - methods Spectroscopy, Fourier Transform Infrared - methods Spectroscopy, Fourier Transform Infrared - utilization
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