Pulmonary hypertension in rheumatic mitral stenosis revisited
Background In patients with mitral stenosis (MS), pulmonary hypertension (PH) is a significant contributor to the associated morbidity. We aimed to study factors associated with the presence of significant PH (sPH) and whether incorporating body surface area (BSA) in the mitral valve area (MVA) woul...
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| Veröffentlicht in: | Herz 2017-12, Vol.42 (8), p.746-751 |
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| creator | Pourafkari, L. Ghaffari, S. Ahmadi, M. Tajlil, A. Aslanabadi, N. Nader, N. D. |
| description | Background
In patients with mitral stenosis (MS), pulmonary hypertension (PH) is a significant contributor to the associated morbidity. We aimed to study factors associated with the presence of significant PH (sPH) and whether incorporating body surface area (BSA) in the mitral valve area (MVA) would improve the predictive value of the latter.
Methods
The medical records of 558 patients with severe MS undergoing percutaneous balloon mitral commissurotomy were evaluated over a period of 8 years. Factors associated with the presence of significant PH (sPH) defined as mPAP ≥ 40 mm Hg were examined.
Results
A total of 558 patients (423 women) were enrolled. Overall, 153 (27%) patients had sPH. Patients with sPH were similar to the rest of the subjects in terms of demographics, body habitus, blood group, and incidence of atrial fibrillation. Among echocardiographic findings, absolute MVA, indexed MVA, and mean transmitral valve gradient were associated with the presence of sPH. Transmitral valve gradient during right heart catheterization had the highest area under the curve for an association with sPH.
Conclusion
Age, gender, heart rhythm, and blood group were not associated with the presence of sPH in severe MS. The predictive value of the indexed MVA for the presence of sPH was not higher than that of absolute MVA. |
| doi_str_mv | 10.1007/s00059-016-4509-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1847883958</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1847883958</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-ec18f4c2f9950adccfdbf91f32d60596f323fc5e94973ad4beecfc279b33b8ea3</originalsourceid><addsrcrecordid>eNp1kE1LAzEQhoMotlZ_gBdZ8OIlms_dzcGDFL-goAc9h2x2YlP2oya7Qv-9KVURwdME5pl3Jg9Cp5RcUkKKq0gIkQoTmmMhicJsD01pTiXOc8X20ZRwQbBSvJigoxhXhFCpGDlEE1YoVkolpuj6eWzavjNhky03awgDdNH3Xea7LCxhbM3gbdb6IZgmi6nZRx-zAB8--gHqY3TgTBPh5KvO0Ovd7cv8AS-e7h_nNwtsecEGDJaWTljmlJLE1Na6unKKOs7qPH0gTw_urAQlVMFNLSoA62w6suK8KsHwGbrY5a5D_z5CHHTro4WmMR30Y9S0FEVZciXLhJ7_QVf9GLp0naaqYErIgm0puqNs6GMM4PQ6-DZZ0JTorVu9c6uTW711q1maOftKHqsW6p-Jb5kJYDsgplb3BuHX6n9TPwHCCoU2</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1972945728</pqid></control><display><type>article</type><title>Pulmonary hypertension in rheumatic mitral stenosis revisited</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Pourafkari, L. ; Ghaffari, S. ; Ahmadi, M. ; Tajlil, A. ; Aslanabadi, N. ; Nader, N. D.</creator><creatorcontrib>Pourafkari, L. ; Ghaffari, S. ; Ahmadi, M. ; Tajlil, A. ; Aslanabadi, N. ; Nader, N. D.</creatorcontrib><description>Background
In patients with mitral stenosis (MS), pulmonary hypertension (PH) is a significant contributor to the associated morbidity. We aimed to study factors associated with the presence of significant PH (sPH) and whether incorporating body surface area (BSA) in the mitral valve area (MVA) would improve the predictive value of the latter.
Methods
The medical records of 558 patients with severe MS undergoing percutaneous balloon mitral commissurotomy were evaluated over a period of 8 years. Factors associated with the presence of significant PH (sPH) defined as mPAP ≥ 40 mm Hg were examined.
Results
A total of 558 patients (423 women) were enrolled. Overall, 153 (27%) patients had sPH. Patients with sPH were similar to the rest of the subjects in terms of demographics, body habitus, blood group, and incidence of atrial fibrillation. Among echocardiographic findings, absolute MVA, indexed MVA, and mean transmitral valve gradient were associated with the presence of sPH. Transmitral valve gradient during right heart catheterization had the highest area under the curve for an association with sPH.
Conclusion
Age, gender, heart rhythm, and blood group were not associated with the presence of sPH in severe MS. The predictive value of the indexed MVA for the presence of sPH was not higher than that of absolute MVA.</description><identifier>ISSN: 0340-9937</identifier><identifier>EISSN: 1615-6692</identifier><identifier>DOI: 10.1007/s00059-016-4509-2</identifier><identifier>PMID: 27928594</identifier><language>eng</language><publisher>Munich: Springer Medizin</publisher><subject>Adult ; Balloon treatment ; Balloon Valvuloplasty - methods ; Blood groups ; Body Surface Area ; Cardiology ; Catheterization ; Demographics ; Demography ; Echocardiography ; Female ; Fibrillation ; Heart ; Hemodynamics ; Hemodynamics - physiology ; Humans ; Hypertension ; Hypertension, Pulmonary - diagnosis ; Hypertension, Pulmonary - physiopathology ; Hypertension, Pulmonary - therapy ; Internal Medicine ; Male ; Medical records ; Medicine ; Medicine & Public Health ; Mercury ; Middle Aged ; Mitral valve ; Mitral Valve - physiopathology ; Mitral Valve Stenosis - diagnosis ; Mitral Valve Stenosis - physiopathology ; Mitral Valve Stenosis - therapy ; Morbidity ; Original Articles ; Patients ; Predictive Value of Tests ; Pulmonary hypertension ; Retrospective Studies ; Rheumatic Heart Disease - diagnosis ; Rheumatic Heart Disease - physiopathology ; Rheumatic Heart Disease - therapy ; Stenosis</subject><ispartof>Herz, 2017-12, Vol.42 (8), p.746-751</ispartof><rights>Springer Medizin Verlag Berlin (outside the USA) 2016</rights><rights>Herz is a copyright of Springer, (2016). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-ec18f4c2f9950adccfdbf91f32d60596f323fc5e94973ad4beecfc279b33b8ea3</citedby><cites>FETCH-LOGICAL-c372t-ec18f4c2f9950adccfdbf91f32d60596f323fc5e94973ad4beecfc279b33b8ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00059-016-4509-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00059-016-4509-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27926,27927,41490,42559,51321</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27928594$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pourafkari, L.</creatorcontrib><creatorcontrib>Ghaffari, S.</creatorcontrib><creatorcontrib>Ahmadi, M.</creatorcontrib><creatorcontrib>Tajlil, A.</creatorcontrib><creatorcontrib>Aslanabadi, N.</creatorcontrib><creatorcontrib>Nader, N. D.</creatorcontrib><title>Pulmonary hypertension in rheumatic mitral stenosis revisited</title><title>Herz</title><addtitle>Herz</addtitle><addtitle>Herz</addtitle><description>Background
In patients with mitral stenosis (MS), pulmonary hypertension (PH) is a significant contributor to the associated morbidity. We aimed to study factors associated with the presence of significant PH (sPH) and whether incorporating body surface area (BSA) in the mitral valve area (MVA) would improve the predictive value of the latter.
Methods
The medical records of 558 patients with severe MS undergoing percutaneous balloon mitral commissurotomy were evaluated over a period of 8 years. Factors associated with the presence of significant PH (sPH) defined as mPAP ≥ 40 mm Hg were examined.
Results
A total of 558 patients (423 women) were enrolled. Overall, 153 (27%) patients had sPH. Patients with sPH were similar to the rest of the subjects in terms of demographics, body habitus, blood group, and incidence of atrial fibrillation. Among echocardiographic findings, absolute MVA, indexed MVA, and mean transmitral valve gradient were associated with the presence of sPH. Transmitral valve gradient during right heart catheterization had the highest area under the curve for an association with sPH.
Conclusion
Age, gender, heart rhythm, and blood group were not associated with the presence of sPH in severe MS. The predictive value of the indexed MVA for the presence of sPH was not higher than that of absolute MVA.</description><subject>Adult</subject><subject>Balloon treatment</subject><subject>Balloon Valvuloplasty - methods</subject><subject>Blood groups</subject><subject>Body Surface Area</subject><subject>Cardiology</subject><subject>Catheterization</subject><subject>Demographics</subject><subject>Demography</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Fibrillation</subject><subject>Heart</subject><subject>Hemodynamics</subject><subject>Hemodynamics - physiology</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Hypertension, Pulmonary - diagnosis</subject><subject>Hypertension, Pulmonary - physiopathology</subject><subject>Hypertension, Pulmonary - therapy</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mercury</subject><subject>Middle Aged</subject><subject>Mitral valve</subject><subject>Mitral Valve - physiopathology</subject><subject>Mitral Valve Stenosis - diagnosis</subject><subject>Mitral Valve Stenosis - physiopathology</subject><subject>Mitral Valve Stenosis - therapy</subject><subject>Morbidity</subject><subject>Original Articles</subject><subject>Patients</subject><subject>Predictive Value of Tests</subject><subject>Pulmonary hypertension</subject><subject>Retrospective Studies</subject><subject>Rheumatic Heart Disease - diagnosis</subject><subject>Rheumatic Heart Disease - physiopathology</subject><subject>Rheumatic Heart Disease - therapy</subject><subject>Stenosis</subject><issn>0340-9937</issn><issn>1615-6692</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kE1LAzEQhoMotlZ_gBdZ8OIlms_dzcGDFL-goAc9h2x2YlP2oya7Qv-9KVURwdME5pl3Jg9Cp5RcUkKKq0gIkQoTmmMhicJsD01pTiXOc8X20ZRwQbBSvJigoxhXhFCpGDlEE1YoVkolpuj6eWzavjNhky03awgDdNH3Xea7LCxhbM3gbdb6IZgmi6nZRx-zAB8--gHqY3TgTBPh5KvO0Ovd7cv8AS-e7h_nNwtsecEGDJaWTljmlJLE1Na6unKKOs7qPH0gTw_urAQlVMFNLSoA62w6suK8KsHwGbrY5a5D_z5CHHTro4WmMR30Y9S0FEVZciXLhJ7_QVf9GLp0naaqYErIgm0puqNs6GMM4PQ6-DZZ0JTorVu9c6uTW711q1maOftKHqsW6p-Jb5kJYDsgplb3BuHX6n9TPwHCCoU2</recordid><startdate>20171201</startdate><enddate>20171201</enddate><creator>Pourafkari, L.</creator><creator>Ghaffari, S.</creator><creator>Ahmadi, M.</creator><creator>Tajlil, A.</creator><creator>Aslanabadi, N.</creator><creator>Nader, N. D.</creator><general>Springer Medizin</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20171201</creationdate><title>Pulmonary hypertension in rheumatic mitral stenosis revisited</title><author>Pourafkari, L. ; Ghaffari, S. ; Ahmadi, M. ; Tajlil, A. ; Aslanabadi, N. ; Nader, N. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-ec18f4c2f9950adccfdbf91f32d60596f323fc5e94973ad4beecfc279b33b8ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Balloon treatment</topic><topic>Balloon Valvuloplasty - methods</topic><topic>Blood groups</topic><topic>Body Surface Area</topic><topic>Cardiology</topic><topic>Catheterization</topic><topic>Demographics</topic><topic>Demography</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Fibrillation</topic><topic>Heart</topic><topic>Hemodynamics</topic><topic>Hemodynamics - physiology</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Hypertension, Pulmonary - diagnosis</topic><topic>Hypertension, Pulmonary - physiopathology</topic><topic>Hypertension, Pulmonary - therapy</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mercury</topic><topic>Middle Aged</topic><topic>Mitral valve</topic><topic>Mitral Valve - physiopathology</topic><topic>Mitral Valve Stenosis - diagnosis</topic><topic>Mitral Valve Stenosis - physiopathology</topic><topic>Mitral Valve Stenosis - therapy</topic><topic>Morbidity</topic><topic>Original Articles</topic><topic>Patients</topic><topic>Predictive Value of Tests</topic><topic>Pulmonary hypertension</topic><topic>Retrospective Studies</topic><topic>Rheumatic Heart Disease - diagnosis</topic><topic>Rheumatic Heart Disease - physiopathology</topic><topic>Rheumatic Heart Disease - therapy</topic><topic>Stenosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pourafkari, L.</creatorcontrib><creatorcontrib>Ghaffari, S.</creatorcontrib><creatorcontrib>Ahmadi, M.</creatorcontrib><creatorcontrib>Tajlil, A.</creatorcontrib><creatorcontrib>Aslanabadi, N.</creatorcontrib><creatorcontrib>Nader, N. D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Herz</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pourafkari, L.</au><au>Ghaffari, S.</au><au>Ahmadi, M.</au><au>Tajlil, A.</au><au>Aslanabadi, N.</au><au>Nader, N. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary hypertension in rheumatic mitral stenosis revisited</atitle><jtitle>Herz</jtitle><stitle>Herz</stitle><addtitle>Herz</addtitle><date>2017-12-01</date><risdate>2017</risdate><volume>42</volume><issue>8</issue><spage>746</spage><epage>751</epage><pages>746-751</pages><issn>0340-9937</issn><eissn>1615-6692</eissn><abstract>Background
In patients with mitral stenosis (MS), pulmonary hypertension (PH) is a significant contributor to the associated morbidity. We aimed to study factors associated with the presence of significant PH (sPH) and whether incorporating body surface area (BSA) in the mitral valve area (MVA) would improve the predictive value of the latter.
Methods
The medical records of 558 patients with severe MS undergoing percutaneous balloon mitral commissurotomy were evaluated over a period of 8 years. Factors associated with the presence of significant PH (sPH) defined as mPAP ≥ 40 mm Hg were examined.
Results
A total of 558 patients (423 women) were enrolled. Overall, 153 (27%) patients had sPH. Patients with sPH were similar to the rest of the subjects in terms of demographics, body habitus, blood group, and incidence of atrial fibrillation. Among echocardiographic findings, absolute MVA, indexed MVA, and mean transmitral valve gradient were associated with the presence of sPH. Transmitral valve gradient during right heart catheterization had the highest area under the curve for an association with sPH.
Conclusion
Age, gender, heart rhythm, and blood group were not associated with the presence of sPH in severe MS. The predictive value of the indexed MVA for the presence of sPH was not higher than that of absolute MVA.</abstract><cop>Munich</cop><pub>Springer Medizin</pub><pmid>27928594</pmid><doi>10.1007/s00059-016-4509-2</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Adult Balloon treatment Balloon Valvuloplasty - methods Blood groups Body Surface Area Cardiology Catheterization Demographics Demography Echocardiography Female Fibrillation Heart Hemodynamics Hemodynamics - physiology Humans Hypertension Hypertension, Pulmonary - diagnosis Hypertension, Pulmonary - physiopathology Hypertension, Pulmonary - therapy Internal Medicine Male Medical records Medicine Medicine & Public Health Mercury Middle Aged Mitral valve Mitral Valve - physiopathology Mitral Valve Stenosis - diagnosis Mitral Valve Stenosis - physiopathology Mitral Valve Stenosis - therapy Morbidity Original Articles Patients Predictive Value of Tests Pulmonary hypertension Retrospective Studies Rheumatic Heart Disease - diagnosis Rheumatic Heart Disease - physiopathology Rheumatic Heart Disease - therapy Stenosis |
| title | Pulmonary hypertension in rheumatic mitral stenosis revisited |
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