Molecular Testing of Thyroid Nodules: A Review of Current Available Tests for Fine-Needle Aspiration Specimens

- Fine-needle aspiration of thyroid nodules is a reliable diagnostic method to determine the nature of thyroid nodules. Nonetheless, indeterminate cytology diagnoses remain a diagnostic challenge. The development of multiplex molecular techniques and the identification of genetic alterations associa...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2016-12, Vol.140 (12), p.1338-1344
Hauptverfasser:	Zhang, Ming, Lin, Oscar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Follicular - diagnosis Adenocarcinoma, Follicular - genetics Adenocarcinoma, Follicular - metabolism Adenocarcinoma, Follicular - pathology Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Biopsy, Fine-Needle Cytogenetic Analysis - trends Diagnosis Diagnosis, Differential Gene expression Gene Expression Regulation, Neoplastic Gene mutation Humans Molecular Diagnostic Techniques - trends Mutation Neoplasm Grading Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Practice Guidelines as Topic Predictive Value of Tests Societies, Medical Thyroid cancer Thyroid Gland - metabolism Thyroid Gland - pathology Thyroid Nodule - diagnosis Thyroid Nodule - genetics Thyroid Nodule - metabolism Thyroid Nodule - pathology Translocation, Genetic United States
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