Sevoflurane Exposure during the Critical Period Affects Synaptic Transmission and Mitochondrial Respiration but Not Long-term Behavior in Mice

BACKGROUND:Anesthesia during the synaptogenic period induces dendritic spine formation, which may affect neurodevelopment. The authors, therefore, evaluated whether changes in synaptic transmission after dendritic spine formation induced by sevoflurane were associated with long-term behavioral chang...

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Veröffentlicht in:	Anesthesiology (Philadelphia) 2017-02, Vol.126 (2), p.288-299
Hauptverfasser:	Chung, Woosuk, Ryu, Min Jeong, Heo, Jun Young, Lee, Soomin, Yoon, Seunghwan, Park, Haram, Park, Sangil, Kim, Yangsik, Kim, Yoon Hee, Yoon, Seok Hwa, Shin, Yong Sup, Lee, Won Hyung, Ju, Xianshu, Kweon, Gi Ryang, Ko, Youngkwon
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics, Inhalation - pharmacology Animals Behavior, Animal - drug effects Female Male Methyl Ethers - pharmacology Mice Mice, Inbred C57BL Mitochondria - drug effects Sex Factors Synaptic Transmission - drug effects
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