Gatifloxacin-Associated Corrected QT Interval Prolongation, Torsades de Pointes, and Ventricular Fibrillation in Patients with Known Risk Factors
Drugs not commonly considered to be cardioactive agents have been reported to cause prolongation of the corrected QT interval with resultant torsades de pointes or ventricular fibrillation. We report 4 cases of gatifloxacin-associated cardiac toxicity in patients with known risk factors for this adv...
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| Veröffentlicht in: | Clinical infectious diseases 2002-03, Vol.34 (6), p.861-863 |
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| container_end_page | 863 |
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| container_issue | 6 |
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| container_title | Clinical infectious diseases |
| container_volume | 34 |
| creator | Bertino, Joseph S. Owens, Robert C. Carnes, Timothy D. Iannini, Paul B. |
| description | Drugs not commonly considered to be cardioactive agents have been reported to cause prolongation of the corrected QT interval with resultant torsades de pointes or ventricular fibrillation. We report 4 cases of gatifloxacin-associated cardiac toxicity in patients with known risk factors for this adverse event. |
| doi_str_mv | 10.1086/339075 |
| format | Article |
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We report 4 cases of gatifloxacin-associated cardiac toxicity in patients with known risk factors for this adverse event.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Infective Agents - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Brief Reports</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular agents</subject><subject>Congestive heart failure</subject><subject>Dosage</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Female</subject><subject>Fluoroquinolones</subject><subject>Heart</subject><subject>Heart - drug effects</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Long QT Syndrome</subject><subject>Medical sciences</subject><subject>Medications</subject><subject>Middle Aged</subject><subject>Musical intervals</subject><subject>Pharmacology. Drug treatments</subject><subject>Predisposing factors</subject><subject>Risk Factors</subject><subject>Torsades de Pointes</subject><subject>Torsades de Pointes - chemically induced</subject><subject>Toxicity: cardiovascular system</subject><subject>Ventricular fibrillation</subject><subject>Ventricular Fibrillation - chemically induced</subject><issn>1058-4838</issn><issn>1537-6591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM1u1DAUhSMEoj_AEyDkLsqqATv-ibMsI6atqMSAhqrqxrqxHXCbsQc7oeUxeGM8ZNRZsbpHOt899-oUxSuC3xEsxXtKG1zzJ8U-4bQuBW_I06wxlyWTVO4VByndYkyIxPx5sZcnxRJX-8WfMxhc14cH0M6XpykF7WCwBs1CjFZv1JcluvCDjb-gR4sY-uC_553gT9AyxATGJmQsWgSXoXSCwBt0Zf0QnR57iGju2uj6_t8Kch4tssp2Qvdu-IE--XDv0VeX7tAc9JADXxTPOuiTfbmdh8W3-cfl7Ly8_Hx2MTu9LDWr5VBKQW3VyI5LzXDNJKeUypYZaCvGhbC1sbTRxrSt6ABbAqDrDqyWLadgKkoPi7dT7jqGn6NNg1q5pG3-1NswJkUkE0IKsQN1DClF26l1dCuIvxXBalO-msrP4Jtt4tiurNlh27YzcLwFIGnouwheu7TjKGeYV5uLRxMXxvX_j72emNuUW3ukGBOkkSTb5WS7NNiHRxvinRI1rbk6v75R12Q2l8sPV-qG_gWNA7DC</recordid><startdate>20020315</startdate><enddate>20020315</enddate><creator>Bertino, Joseph S.</creator><creator>Owens, Robert C.</creator><creator>Carnes, Timothy D.</creator><creator>Iannini, Paul B.</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>20020315</creationdate><title>Gatifloxacin-Associated Corrected QT Interval Prolongation, Torsades de Pointes, and Ventricular Fibrillation in Patients with Known Risk Factors</title><author>Bertino, Joseph S. ; Owens, Robert C. ; Carnes, Timothy D. ; Iannini, Paul B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-863e298f58c4074853338b4dab24566e7de39cddbb6fa0e1aac7faec8b53ad233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Infective Agents - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Brief Reports</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular agents</topic><topic>Congestive heart failure</topic><topic>Dosage</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Female</topic><topic>Fluoroquinolones</topic><topic>Heart</topic><topic>Heart - drug effects</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Long QT Syndrome</topic><topic>Medical sciences</topic><topic>Medications</topic><topic>Middle Aged</topic><topic>Musical intervals</topic><topic>Pharmacology. Drug treatments</topic><topic>Predisposing factors</topic><topic>Risk Factors</topic><topic>Torsades de Pointes</topic><topic>Torsades de Pointes - chemically induced</topic><topic>Toxicity: cardiovascular system</topic><topic>Ventricular fibrillation</topic><topic>Ventricular Fibrillation - chemically induced</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bertino, Joseph S.</creatorcontrib><creatorcontrib>Owens, Robert C.</creatorcontrib><creatorcontrib>Carnes, Timothy D.</creatorcontrib><creatorcontrib>Iannini, Paul B.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bertino, Joseph S.</au><au>Owens, Robert C.</au><au>Carnes, Timothy D.</au><au>Iannini, Paul B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gatifloxacin-Associated Corrected QT Interval Prolongation, Torsades de Pointes, and Ventricular Fibrillation in Patients with Known Risk Factors</atitle><jtitle>Clinical infectious diseases</jtitle><stitle>Clinical Infectious Diseases</stitle><addtitle>Clinical Infectious Diseases</addtitle><date>2002-03-15</date><risdate>2002</risdate><volume>34</volume><issue>6</issue><spage>861</spage><epage>863</epage><pages>861-863</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>Drugs not commonly considered to be cardioactive agents have been reported to cause prolongation of the corrected QT interval with resultant torsades de pointes or ventricular fibrillation. 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| fulltext | fulltext |
| identifier | ISSN: 1058-4838 |
| ispartof | Clinical infectious diseases, 2002-03, Vol.34 (6), p.861-863 |
| issn | 1058-4838 1537-6591 |
| language | eng |
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| source | MEDLINE; Oxford Academic Journals (OUP); JSTOR; EZB Electronic Journals Library |
| subjects | Aged Aged, 80 and over Anti-Infective Agents - adverse effects Biological and medical sciences Brief Reports Cardiac dysrhythmias Cardiology. Vascular system Cardiovascular agents Congestive heart failure Dosage Drug toxicity and drugs side effects treatment Female Fluoroquinolones Heart Heart - drug effects Humans Infectious diseases Long QT Syndrome Medical sciences Medications Middle Aged Musical intervals Pharmacology. Drug treatments Predisposing factors Risk Factors Torsades de Pointes Torsades de Pointes - chemically induced Toxicity: cardiovascular system Ventricular fibrillation Ventricular Fibrillation - chemically induced |
| title | Gatifloxacin-Associated Corrected QT Interval Prolongation, Torsades de Pointes, and Ventricular Fibrillation in Patients with Known Risk Factors |
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