In vitro assessment of an antibacterial quaternary ammonium-based polymer loaded with chlorhexidine for the coating of polypropylene prosthetic meshes

Purpose This study assesses the use of an absorbable polymer loaded with chlorhexidine (CHX) as an antibacterial coating for polypropylene (PP) meshes employed in hernia repair. Methods The polymer N,N -dimethyl- N -benzyl- N -(2-methacryloyloxyethyl) ammonium bromide was loaded with CHX (1 % w/w)....

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Veröffentlicht in:	Hernia : the journal of hernias and abdominal wall surgery 2016-12, Vol.20 (6), p.869-878
Hauptverfasser:	Pérez-Köhler, B., Fernández-Gutiérrez, M., Pascual, G., García-Moreno, F., San Román, J., Bellón, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Absorbable Implants Anti-Bacterial Agents - administration & dosage Anti-Infective Agents, Local - administration & dosage Bacterial Adhesion - drug effects Chlorhexidine - administration & dosage Coated Materials, Biocompatible Escherichia coli Escherichia coli - drug effects Herniorrhaphy - instrumentation Herniorrhaphy - methods In Vitro Techniques Medicine Medicine & Public Health Microbial Sensitivity Tests Microscopy, Electron, Scanning Original Article Polymers Polypropylenes - administration & dosage Prosthesis-Related Infections - etiology Prosthesis-Related Infections - prevention & control Quaternary Ammonium Compounds - administration & dosage Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus epidermidis Staphylococcus epidermidis - drug effects Staphylococcus epidermidis - physiology Surgical Mesh - microbiology
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