The asphericity of the metabolic tumour volume in NSCLC: correlation with histopathology and molecular markers

Purpose Asphericity (ASP) is a tumour shape descriptor based on the PET image. It quantitates the deviation from spherical of the shape of the metabolic tumour volume (MTV). In order to identify its biological correlates, we investigated the relationship between ASP and clinically relevant histopath...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2016-12, Vol.43 (13), p.2360-2373
Hauptverfasser:	Apostolova, Ivayla, Ego, Kilian, Steffen, Ingo G., Buchert, Ralph, Wertzel, Heinz, Achenbach, H. Jost, Riedel, Sandra, Schreiber, Jens, Schultz, Meinald, Furth, Christian, Derlin, Thorsten, Amthauer, Holger, Hofheinz, Frank, Kalinski, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Algorithms Biomarkers, Tumor - metabolism Carcinoma, Non-Small-Cell Lung - diagnostic imaging Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Cardiology Female Fluorodeoxyglucose F18 - pharmacokinetics Histopathology Humans Image Interpretation, Computer-Assisted - methods Imaging Lung cancer Lung Neoplasms - diagnostic imaging Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Medicine Medicine & Public Health Middle Aged Molecular biology Neoplasm Staging Nuclear Medicine Oncology Original Article Orthopedics Positron-Emission Tomography - methods Radiology Radiopharmaceuticals - pharmacokinetics Reproducibility of Results Sensitivity and Specificity Tomography Tumor Burden Tumors
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