The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy
Purpose The aim was to determine the dose-specific incidence and predictors of seed loss/migration after permanent seed implantation (PI) for localized prostate cancer. Materials and methods The records of 79 patients with T1c–T3a prostate cancer who underwent prostate brachytherapy with loose iodin...
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| Veröffentlicht in: | Japanese journal of radiology 2016-11, Vol.34 (11), p.718-723 |
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| container_title | Japanese journal of radiology |
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| creator | Hirose, Katsumi Aoki, Masahiko Sato, Mariko Akimoto, Hiroyoshi Hashimoto, Yasuhiro Imai, Atsushi Kamimura, Noritaka Kawaguchi, Hideo Hatayama, Yoshiomi Fujioka, Ichitaro Tanaka, Mitsuki Ohyama, Chikara Takai, Yoshihiro |
| description | Purpose
The aim was to determine the dose-specific incidence and predictors of seed loss/migration after permanent seed implantation (PI) for localized prostate cancer.
Materials and methods
The records of 79 patients with T1c–T3a prostate cancer who underwent prostate brachytherapy with loose iodine-125 seeds were retrospectively reviewed. Of these patients, 33 with low or intermediate risk underwent PI with the prescribed dose of 160 Gy for the clinical target volume (CTV), and 46 with high risk underwent PI with 110 Gy for the CTV followed by external beam radiotherapy (EBRT) with 45 Gy. Each CTV was defined as a contoured prostate. After PI, the incidence of seed loss/migration was assessed by a series of radiographs.
Results
Seed migration occurred in 22 (0.479 %) of 4589 implanted seeds 1 month after implantation. In PI alone, the number of needles (
P
= 0.081) and the number of seeds (
P
= 0.071) showed a trend for a difference between those with and without seed loss. In PI + EBRT, there was a significant difference in the discrepancy between the seed numbers calculated by the nomogram and actually implanted (
P
= 0.032).
Conclusions
It is suggested that the discrepancy in seed numbers might be the predictor for seed migration in PI with 110 Gy. |
| doi_str_mv | 10.1007/s11604-016-0578-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1846412810</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4242237191</sourcerecordid><originalsourceid>FETCH-LOGICAL-c495t-ad754409a7c8f9b7695e2f5e9bb43992626055e2ecca81d4ee57344a4973a0923</originalsourceid><addsrcrecordid>eNqNkd1qFTEUhQex2Nr6AN5IwBtvRpNMfi-l-AcFb1roXchk9vSkzpmM2TmV8xI-szmdWkQQhISE7G-tnWQ1zUtG3zJK9TtkTFHRUqZaKrVp9ZPmhBmlW0bN9dPHvWbHzXPEW0qV6IR41hxzrTpmDD9pfl5ugGQoOeECocQ7IH720x4jkjSScl-dfIlpxk1cSA_lB8BMlgwYcuxhIEPCg2ggOeI3MvpQUiZjnQi1uo03-V5OYh1piDO0jMtqkLD4AqTPPmz2tVH2y_6sORr9hPDiYT1trj5-uDz_3F58_fTl_P1FG4SVpfWDlkJQ63Uwo-21shL4KMH2veis5YorKusRhOANGwSA1PXlXljdeWp5d9q8WX3rNb7vAIvbRgwwTX6GtEPHjFCCccPof6Cd5kZKLSr6-i_0Nu1y_c6VqjkpISvFVirUL8AMo1ty3Pq8d4y6Q65uzdVV3h1ydbpqXj047_otDI-K30FWgK8A1tJ8A_mP1v90_QXbZK6n</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1837016645</pqid></control><display><type>article</type><title>The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Hirose, Katsumi ; Aoki, Masahiko ; Sato, Mariko ; Akimoto, Hiroyoshi ; Hashimoto, Yasuhiro ; Imai, Atsushi ; Kamimura, Noritaka ; Kawaguchi, Hideo ; Hatayama, Yoshiomi ; Fujioka, Ichitaro ; Tanaka, Mitsuki ; Ohyama, Chikara ; Takai, Yoshihiro</creator><creatorcontrib>Hirose, Katsumi ; Aoki, Masahiko ; Sato, Mariko ; Akimoto, Hiroyoshi ; Hashimoto, Yasuhiro ; Imai, Atsushi ; Kamimura, Noritaka ; Kawaguchi, Hideo ; Hatayama, Yoshiomi ; Fujioka, Ichitaro ; Tanaka, Mitsuki ; Ohyama, Chikara ; Takai, Yoshihiro</creatorcontrib><description>Purpose
The aim was to determine the dose-specific incidence and predictors of seed loss/migration after permanent seed implantation (PI) for localized prostate cancer.
Materials and methods
The records of 79 patients with T1c–T3a prostate cancer who underwent prostate brachytherapy with loose iodine-125 seeds were retrospectively reviewed. Of these patients, 33 with low or intermediate risk underwent PI with the prescribed dose of 160 Gy for the clinical target volume (CTV), and 46 with high risk underwent PI with 110 Gy for the CTV followed by external beam radiotherapy (EBRT) with 45 Gy. Each CTV was defined as a contoured prostate. After PI, the incidence of seed loss/migration was assessed by a series of radiographs.
Results
Seed migration occurred in 22 (0.479 %) of 4589 implanted seeds 1 month after implantation. In PI alone, the number of needles (
P
= 0.081) and the number of seeds (
P
= 0.071) showed a trend for a difference between those with and without seed loss. In PI + EBRT, there was a significant difference in the discrepancy between the seed numbers calculated by the nomogram and actually implanted (
P
= 0.032).
Conclusions
It is suggested that the discrepancy in seed numbers might be the predictor for seed migration in PI with 110 Gy.</description><identifier>ISSN: 1867-1071</identifier><identifier>EISSN: 1867-108X</identifier><identifier>DOI: 10.1007/s11604-016-0578-7</identifier><identifier>PMID: 27631882</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Aged ; Brachytherapy - instrumentation ; Dose-Response Relationship, Radiation ; Foreign-Body Migration - diagnostic imaging ; Humans ; Imaging ; Iodine Radioisotopes - therapeutic use ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Nuclear Medicine ; Original Article ; Prostatic Neoplasms - radiotherapy ; Radiology ; Radiotherapy ; Radiotherapy Dosage ; Retrospective Studies ; Risk Factors</subject><ispartof>Japanese journal of radiology, 2016-11, Vol.34 (11), p.718-723</ispartof><rights>Japan Radiological Society 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-ad754409a7c8f9b7695e2f5e9bb43992626055e2ecca81d4ee57344a4973a0923</citedby><cites>FETCH-LOGICAL-c495t-ad754409a7c8f9b7695e2f5e9bb43992626055e2ecca81d4ee57344a4973a0923</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11604-016-0578-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11604-016-0578-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27631882$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hirose, Katsumi</creatorcontrib><creatorcontrib>Aoki, Masahiko</creatorcontrib><creatorcontrib>Sato, Mariko</creatorcontrib><creatorcontrib>Akimoto, Hiroyoshi</creatorcontrib><creatorcontrib>Hashimoto, Yasuhiro</creatorcontrib><creatorcontrib>Imai, Atsushi</creatorcontrib><creatorcontrib>Kamimura, Noritaka</creatorcontrib><creatorcontrib>Kawaguchi, Hideo</creatorcontrib><creatorcontrib>Hatayama, Yoshiomi</creatorcontrib><creatorcontrib>Fujioka, Ichitaro</creatorcontrib><creatorcontrib>Tanaka, Mitsuki</creatorcontrib><creatorcontrib>Ohyama, Chikara</creatorcontrib><creatorcontrib>Takai, Yoshihiro</creatorcontrib><title>The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy</title><title>Japanese journal of radiology</title><addtitle>Jpn J Radiol</addtitle><addtitle>Jpn J Radiol</addtitle><description>Purpose
The aim was to determine the dose-specific incidence and predictors of seed loss/migration after permanent seed implantation (PI) for localized prostate cancer.
Materials and methods
The records of 79 patients with T1c–T3a prostate cancer who underwent prostate brachytherapy with loose iodine-125 seeds were retrospectively reviewed. Of these patients, 33 with low or intermediate risk underwent PI with the prescribed dose of 160 Gy for the clinical target volume (CTV), and 46 with high risk underwent PI with 110 Gy for the CTV followed by external beam radiotherapy (EBRT) with 45 Gy. Each CTV was defined as a contoured prostate. After PI, the incidence of seed loss/migration was assessed by a series of radiographs.
Results
Seed migration occurred in 22 (0.479 %) of 4589 implanted seeds 1 month after implantation. In PI alone, the number of needles (
P
= 0.081) and the number of seeds (
P
= 0.071) showed a trend for a difference between those with and without seed loss. In PI + EBRT, there was a significant difference in the discrepancy between the seed numbers calculated by the nomogram and actually implanted (
P
= 0.032).
Conclusions
It is suggested that the discrepancy in seed numbers might be the predictor for seed migration in PI with 110 Gy.</description><subject>Aged</subject><subject>Brachytherapy - instrumentation</subject><subject>Dose-Response Relationship, Radiation</subject><subject>Foreign-Body Migration - diagnostic imaging</subject><subject>Humans</subject><subject>Imaging</subject><subject>Iodine Radioisotopes - therapeutic use</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Nuclear Medicine</subject><subject>Original Article</subject><subject>Prostatic Neoplasms - radiotherapy</subject><subject>Radiology</subject><subject>Radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><issn>1867-1071</issn><issn>1867-108X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkd1qFTEUhQex2Nr6AN5IwBtvRpNMfi-l-AcFb1roXchk9vSkzpmM2TmV8xI-szmdWkQQhISE7G-tnWQ1zUtG3zJK9TtkTFHRUqZaKrVp9ZPmhBmlW0bN9dPHvWbHzXPEW0qV6IR41hxzrTpmDD9pfl5ugGQoOeECocQ7IH720x4jkjSScl-dfIlpxk1cSA_lB8BMlgwYcuxhIEPCg2ggOeI3MvpQUiZjnQi1uo03-V5OYh1piDO0jMtqkLD4AqTPPmz2tVH2y_6sORr9hPDiYT1trj5-uDz_3F58_fTl_P1FG4SVpfWDlkJQ63Uwo-21shL4KMH2veis5YorKusRhOANGwSA1PXlXljdeWp5d9q8WX3rNb7vAIvbRgwwTX6GtEPHjFCCccPof6Cd5kZKLSr6-i_0Nu1y_c6VqjkpISvFVirUL8AMo1ty3Pq8d4y6Q65uzdVV3h1ydbpqXj047_otDI-K30FWgK8A1tJ8A_mP1v90_QXbZK6n</recordid><startdate>20161101</startdate><enddate>20161101</enddate><creator>Hirose, Katsumi</creator><creator>Aoki, Masahiko</creator><creator>Sato, Mariko</creator><creator>Akimoto, Hiroyoshi</creator><creator>Hashimoto, Yasuhiro</creator><creator>Imai, Atsushi</creator><creator>Kamimura, Noritaka</creator><creator>Kawaguchi, Hideo</creator><creator>Hatayama, Yoshiomi</creator><creator>Fujioka, Ichitaro</creator><creator>Tanaka, Mitsuki</creator><creator>Ohyama, Chikara</creator><creator>Takai, Yoshihiro</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20161101</creationdate><title>The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy</title><author>Hirose, Katsumi ; Aoki, Masahiko ; Sato, Mariko ; Akimoto, Hiroyoshi ; Hashimoto, Yasuhiro ; Imai, Atsushi ; Kamimura, Noritaka ; Kawaguchi, Hideo ; Hatayama, Yoshiomi ; Fujioka, Ichitaro ; Tanaka, Mitsuki ; Ohyama, Chikara ; Takai, Yoshihiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-ad754409a7c8f9b7695e2f5e9bb43992626055e2ecca81d4ee57344a4973a0923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Brachytherapy - instrumentation</topic><topic>Dose-Response Relationship, Radiation</topic><topic>Foreign-Body Migration - diagnostic imaging</topic><topic>Humans</topic><topic>Imaging</topic><topic>Iodine Radioisotopes - therapeutic use</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Nuclear Medicine</topic><topic>Original Article</topic><topic>Prostatic Neoplasms - radiotherapy</topic><topic>Radiology</topic><topic>Radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hirose, Katsumi</creatorcontrib><creatorcontrib>Aoki, Masahiko</creatorcontrib><creatorcontrib>Sato, Mariko</creatorcontrib><creatorcontrib>Akimoto, Hiroyoshi</creatorcontrib><creatorcontrib>Hashimoto, Yasuhiro</creatorcontrib><creatorcontrib>Imai, Atsushi</creatorcontrib><creatorcontrib>Kamimura, Noritaka</creatorcontrib><creatorcontrib>Kawaguchi, Hideo</creatorcontrib><creatorcontrib>Hatayama, Yoshiomi</creatorcontrib><creatorcontrib>Fujioka, Ichitaro</creatorcontrib><creatorcontrib>Tanaka, Mitsuki</creatorcontrib><creatorcontrib>Ohyama, Chikara</creatorcontrib><creatorcontrib>Takai, Yoshihiro</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hirose, Katsumi</au><au>Aoki, Masahiko</au><au>Sato, Mariko</au><au>Akimoto, Hiroyoshi</au><au>Hashimoto, Yasuhiro</au><au>Imai, Atsushi</au><au>Kamimura, Noritaka</au><au>Kawaguchi, Hideo</au><au>Hatayama, Yoshiomi</au><au>Fujioka, Ichitaro</au><au>Tanaka, Mitsuki</au><au>Ohyama, Chikara</au><au>Takai, Yoshihiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy</atitle><jtitle>Japanese journal of radiology</jtitle><stitle>Jpn J Radiol</stitle><addtitle>Jpn J Radiol</addtitle><date>2016-11-01</date><risdate>2016</risdate><volume>34</volume><issue>11</issue><spage>718</spage><epage>723</epage><pages>718-723</pages><issn>1867-1071</issn><eissn>1867-108X</eissn><abstract>Purpose
The aim was to determine the dose-specific incidence and predictors of seed loss/migration after permanent seed implantation (PI) for localized prostate cancer.
Materials and methods
The records of 79 patients with T1c–T3a prostate cancer who underwent prostate brachytherapy with loose iodine-125 seeds were retrospectively reviewed. Of these patients, 33 with low or intermediate risk underwent PI with the prescribed dose of 160 Gy for the clinical target volume (CTV), and 46 with high risk underwent PI with 110 Gy for the CTV followed by external beam radiotherapy (EBRT) with 45 Gy. Each CTV was defined as a contoured prostate. After PI, the incidence of seed loss/migration was assessed by a series of radiographs.
Results
Seed migration occurred in 22 (0.479 %) of 4589 implanted seeds 1 month after implantation. In PI alone, the number of needles (
P
= 0.081) and the number of seeds (
P
= 0.071) showed a trend for a difference between those with and without seed loss. In PI + EBRT, there was a significant difference in the discrepancy between the seed numbers calculated by the nomogram and actually implanted (
P
= 0.032).
Conclusions
It is suggested that the discrepancy in seed numbers might be the predictor for seed migration in PI with 110 Gy.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>27631882</pmid><doi>10.1007/s11604-016-0578-7</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1867-1071 |
| ispartof | Japanese journal of radiology, 2016-11, Vol.34 (11), p.718-723 |
| issn | 1867-1071 1867-108X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1846412810 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Aged Brachytherapy - instrumentation Dose-Response Relationship, Radiation Foreign-Body Migration - diagnostic imaging Humans Imaging Iodine Radioisotopes - therapeutic use Male Medicine Medicine & Public Health Middle Aged Nuclear Medicine Original Article Prostatic Neoplasms - radiotherapy Radiology Radiotherapy Radiotherapy Dosage Retrospective Studies Risk Factors |
| title | The retrospective analysis of the relationship between prescribed dose and risk factor for seed migration in iodine-125 prostate brachytherapy |
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