Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice

Abstract The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice. In order to do s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2016-12, Vol.1652, p.21-29
Hauptverfasser:	Bagosi, Zsolt, Palotai, Miklós, Simon, Balázs, Bokor, Péter, Buzás, András, Balangó, Beáta, Pintér, Dávid, Jászberényi, Miklós, Csabafi, Krisztina, Szabó, Gyula
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - drug therapy Anxiety - etiology Anxiety - metabolism Corticosterone Corticosterone - blood Depression Depression - drug therapy Depression - metabolism Depression - pathology Disease Models, Animal Drug Evaluation, Preclinical Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - metabolism Infusions, Intraventricular Male Mice Motor Activity - drug effects Motor Activity - physiology Neurology Nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Pituitary-Adrenal System - drug effects Pituitary-Adrenal System - metabolism Psychotropic Drugs - administration & dosage Receptors, Corticotropin-Releasing Hormone - agonists Receptors, Corticotropin-Releasing Hormone - metabolism Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - metabolism Substance Withdrawal Syndrome - psychology Tobacco Use Disorder - drug therapy Tobacco Use Disorder - metabolism Tobacco Use Disorder - psychology Urocortin Urocortins - administration & dosage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!