Abstract 4630: The pan-PIM inhibitor PIM447 enhances the antitumor activity of lenalidomide in multiple myeloma cells via synergistic inhibition of c-MYC

Introduction: Immunomodulatory drugs (IMiDs) thalidomide, lenalidomide and pomalidomide have significantly contributed to improved overall survivals in multiple myeloma (MM) patients. However, cure remains an elusive goal for the vast majority of MM patients and novel combination regimens are needed...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.4630-4630
Hauptverfasser:	Hao, Huaixiang, Wang, Dannie, Vanasse, Gary, Caponigro, Giordano
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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