Correlated light and electron microscopy: ultrastructure lights up

Correlated light and electron microscopy (CLEM) gives context to biomolecules studied with fluorescence microscopy. This Review discusses recent improvements and guides readers on probes, instrumentation and sample preparation to implement CLEM. Microscopy has gone hand in hand with the study of liv...

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Veröffentlicht in:	Nature methods 2015-06, Vol.12 (6), p.503-513
Hauptverfasser:	de Boer, Pascal, Hoogenboom, Jacob P, Giepmans, Ben N G
Format:	Artikel
Sprache:	eng
Schlagworte:	14 14/19 14/28 14/69 631/1647/328 Animals Bioinformatics Biological Microscopy Biological Techniques Biology Biomedical Engineering/Biotechnology Cells - ultrastructure Comparative analysis Dyes Electron microscopy Fluorescence Fluorescence microscopy Humans Life Sciences Light microscopy Methods Microorganisms Microscopy Microscopy, Electron - methods Microscopy, Fluorescence - methods Probes Proteomics review-article Staining and Labeling
Online-Zugang:	Volltext
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