Identification of sea bass pIgR shows its interaction with vitellogenin inducing antibody-like activities in HEK 293T cells

Fish vitellogenin (Vg) has been shown to mediate the phagocytosis via interaction with a Fcγ-like phagocytic receptor on macrophages, but identification of such a receptor and its functional characterization remains lacking. In this study, we isolated a cDNA of polymeric immunoglobulin receptor (pIg...

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Veröffentlicht in:	Fish & shellfish immunology 2017-04, Vol.63, p.394-404
Hauptverfasser:	Yang, Shuangshuang, Liu, Shousheng, Qu, Baozhen, Dong, Yuan, Zhang, Shicui
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bass - genetics Bass - immunology Bass - metabolism Cloning, Molecular DNA, Complementary - genetics DNA, Complementary - metabolism Fish Proteins - chemistry Fish Proteins - genetics Fish Proteins - metabolism Gene Expression Regulation HEK293 Cells Humans IgG IgM Immunity, Innate Organ Specificity Phylogeny Polymeric immunoglobulin receptor Protein Domains Real-Time Polymerase Chain Reaction - veterinary Receptors, Polymeric Immunoglobulin - chemistry Receptors, Polymeric Immunoglobulin - genetics Receptors, Polymeric Immunoglobulin - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Sea bass Sequence Alignment - veterinary Vitellogenin
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