Effect of sodium accumulation on heterotrophic growth and polyhydroxybutyrate (PHB) production by Cupriavidus necator

•A mechanistic model was developed to evaluate the effect of Na+ on PHB production.•Model calibration and validation was performed with batch and fed-batch data sets.•Both the steady state and dynamic behavior was effected by Na+.•Non-linear inhibition effect of Na+ on growth and PHB content.•Na+ sh...

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