The therapeutic effect of patient-specific implants in cranioplasty
Abstract Objective Patient specific implants have been used for the reconstruction of large skull bone defects. Several therapeutic effects have been suggested in current literature but were never objectified. The aim of the current study was to evaluate the change in quality of life, pain, aestheti...
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| Veröffentlicht in: | Journal of cranio-maxillo-facial surgery 2017-01, Vol.45 (1), p.82-86 |
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| creator | Zegers, Thomas ter Laak-Poort, Mariel Koper, David Lethaus, Bernd Kessler, Peter |
| description | Abstract Objective Patient specific implants have been used for the reconstruction of large skull bone defects. Several therapeutic effects have been suggested in current literature but were never objectified. The aim of the current study was to evaluate the change in quality of life, pain, aesthetics, and the surgical and medical outcomes after reconstruction of large skull bone defects with titanium or polyetheretherketone (PEEK) implants. Methods We retrospectively evaluated 29 consecutive patients receiving a patient specific skull implant between November 2004 and December 2015. Twenty-one patients received PEEK implants and eight received titanium implants. Data was acquired regarding quality of life, aesthetics, pain, demographics and complications. Quality of life was measured using the Glasgow Benefit Inventory (GBI). Additional questions were asked concerning pain, satisfaction and aesthetics. Results The mean total GBI-score was +26.1 (95%CI 16.8–35.4, p |
| doi_str_mv | 10.1016/j.jcms.2016.10.016 |
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Several therapeutic effects have been suggested in current literature but were never objectified. The aim of the current study was to evaluate the change in quality of life, pain, aesthetics, and the surgical and medical outcomes after reconstruction of large skull bone defects with titanium or polyetheretherketone (PEEK) implants. Methods We retrospectively evaluated 29 consecutive patients receiving a patient specific skull implant between November 2004 and December 2015. Twenty-one patients received PEEK implants and eight received titanium implants. Data was acquired regarding quality of life, aesthetics, pain, demographics and complications. Quality of life was measured using the Glasgow Benefit Inventory (GBI). Additional questions were asked concerning pain, satisfaction and aesthetics. Results The mean total GBI-score was +26.1 (95%CI 16.8–35.4, p < 0.001). Headache complaints or pain in the operation site improved in 75.0% and 77.8% of these patients, respectively. In 8.0% an increase was seen with regard to both variables. Conclusion Reconstruction of skull bone defects with PEEK and titanium patient specific implants gave a statistically significant improvement in quality of life. Furthermore, it decreased pain and headaches and gave aesthetically good results.</description><identifier>ISSN: 1010-5182</identifier><identifier>EISSN: 1878-4119</identifier><identifier>DOI: 10.1016/j.jcms.2016.10.016</identifier><identifier>PMID: 27916400</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Cranioplasty ; Dentistry ; Esthetics ; Female ; Headache ; Humans ; Implants ; Ketones ; Male ; Middle Aged ; Pain, Postoperative - etiology ; Patient Satisfaction ; Polyetheretherketone ; Polyethylene Glycols ; Prostheses and Implants ; Quality of Life ; Reconstructive Surgical Procedures - methods ; Retrospective Studies ; Skull - surgery ; Surgery ; Titanium ; Young Adult</subject><ispartof>Journal of cranio-maxillo-facial surgery, 2017-01, Vol.45 (1), p.82-86</ispartof><rights>European Association for Cranio-Maxillo-Facial Surgery</rights><rights>2016 European Association for Cranio-Maxillo-Facial Surgery</rights><rights>Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c477t-bf394bae5edfdae0bd5ce4af6779834a77b87b5bad3f2ccf4ed45dadd56a26a33</citedby><cites>FETCH-LOGICAL-c477t-bf394bae5edfdae0bd5ce4af6779834a77b87b5bad3f2ccf4ed45dadd56a26a33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jcms.2016.10.016$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27916400$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zegers, Thomas</creatorcontrib><creatorcontrib>ter Laak-Poort, Mariel</creatorcontrib><creatorcontrib>Koper, David</creatorcontrib><creatorcontrib>Lethaus, Bernd</creatorcontrib><creatorcontrib>Kessler, Peter</creatorcontrib><title>The therapeutic effect of patient-specific implants in cranioplasty</title><title>Journal of cranio-maxillo-facial surgery</title><addtitle>J Craniomaxillofac Surg</addtitle><description>Abstract Objective Patient specific implants have been used for the reconstruction of large skull bone defects. Several therapeutic effects have been suggested in current literature but were never objectified. The aim of the current study was to evaluate the change in quality of life, pain, aesthetics, and the surgical and medical outcomes after reconstruction of large skull bone defects with titanium or polyetheretherketone (PEEK) implants. Methods We retrospectively evaluated 29 consecutive patients receiving a patient specific skull implant between November 2004 and December 2015. Twenty-one patients received PEEK implants and eight received titanium implants. Data was acquired regarding quality of life, aesthetics, pain, demographics and complications. Quality of life was measured using the Glasgow Benefit Inventory (GBI). Additional questions were asked concerning pain, satisfaction and aesthetics. Results The mean total GBI-score was +26.1 (95%CI 16.8–35.4, p < 0.001). Headache complaints or pain in the operation site improved in 75.0% and 77.8% of these patients, respectively. In 8.0% an increase was seen with regard to both variables. Conclusion Reconstruction of skull bone defects with PEEK and titanium patient specific implants gave a statistically significant improvement in quality of life. Furthermore, it decreased pain and headaches and gave aesthetically good results.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Cranioplasty</subject><subject>Dentistry</subject><subject>Esthetics</subject><subject>Female</subject><subject>Headache</subject><subject>Humans</subject><subject>Implants</subject><subject>Ketones</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pain, Postoperative - etiology</subject><subject>Patient Satisfaction</subject><subject>Polyetheretherketone</subject><subject>Polyethylene Glycols</subject><subject>Prostheses and Implants</subject><subject>Quality of Life</subject><subject>Reconstructive Surgical Procedures - methods</subject><subject>Retrospective Studies</subject><subject>Skull - surgery</subject><subject>Surgery</subject><subject>Titanium</subject><subject>Young Adult</subject><issn>1010-5182</issn><issn>1878-4119</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtr3DAUhUVp6Eym_QNZFC-z8VSSZcmGUghDHoVAFp2uhSxdMXL8qiQH5t9HZiZZZNHVvbo65yB9F6ErgrcEE_6j3ba6D1ua-jTYpvIJrUklqpwRUn9OPSY4L0lFV-gyhBZjzHFVf0ErKmrCGcZrtNsfIIsH8GqCOTqdgbWgYzbabFLRwRDzMIF2Nl25furUEEPmhkx7NbgxnUM8fkUXVnUBvp3rBv29u93vHvLHp_vfu5vHXDMhYt7YomaNghKMNQpwY0oNTFkuRF0VTAnRVKIpG2UKS7W2DAwrjTKm5IpyVRQbdH3Knfz4b4YQZe-Chi49CsY5SFIxjmlZ1TxJ6Umq_RiCBysn73rlj5JgucCTrVzgyQXeMkslmb6f8-emB_NueaOVBD9PAki_fHHgZdAJkQbjfIImzej-n__rg113bnBadc9whNCOsx8SP0lkoBLLP8v6lu0lK6ac18UrGu6XBA</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Zegers, Thomas</creator><creator>ter Laak-Poort, Mariel</creator><creator>Koper, David</creator><creator>Lethaus, Bernd</creator><creator>Kessler, Peter</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170101</creationdate><title>The therapeutic effect of patient-specific implants in cranioplasty</title><author>Zegers, Thomas ; ter Laak-Poort, Mariel ; Koper, David ; Lethaus, Bernd ; Kessler, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c477t-bf394bae5edfdae0bd5ce4af6779834a77b87b5bad3f2ccf4ed45dadd56a26a33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Cranioplasty</topic><topic>Dentistry</topic><topic>Esthetics</topic><topic>Female</topic><topic>Headache</topic><topic>Humans</topic><topic>Implants</topic><topic>Ketones</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pain, Postoperative - etiology</topic><topic>Patient Satisfaction</topic><topic>Polyetheretherketone</topic><topic>Polyethylene Glycols</topic><topic>Prostheses and Implants</topic><topic>Quality of Life</topic><topic>Reconstructive Surgical Procedures - methods</topic><topic>Retrospective Studies</topic><topic>Skull - surgery</topic><topic>Surgery</topic><topic>Titanium</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zegers, Thomas</creatorcontrib><creatorcontrib>ter Laak-Poort, Mariel</creatorcontrib><creatorcontrib>Koper, David</creatorcontrib><creatorcontrib>Lethaus, Bernd</creatorcontrib><creatorcontrib>Kessler, Peter</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cranio-maxillo-facial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zegers, Thomas</au><au>ter Laak-Poort, Mariel</au><au>Koper, David</au><au>Lethaus, Bernd</au><au>Kessler, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The therapeutic effect of patient-specific implants in cranioplasty</atitle><jtitle>Journal of cranio-maxillo-facial surgery</jtitle><addtitle>J Craniomaxillofac Surg</addtitle><date>2017-01-01</date><risdate>2017</risdate><volume>45</volume><issue>1</issue><spage>82</spage><epage>86</epage><pages>82-86</pages><issn>1010-5182</issn><eissn>1878-4119</eissn><abstract>Abstract Objective Patient specific implants have been used for the reconstruction of large skull bone defects. Several therapeutic effects have been suggested in current literature but were never objectified. The aim of the current study was to evaluate the change in quality of life, pain, aesthetics, and the surgical and medical outcomes after reconstruction of large skull bone defects with titanium or polyetheretherketone (PEEK) implants. Methods We retrospectively evaluated 29 consecutive patients receiving a patient specific skull implant between November 2004 and December 2015. Twenty-one patients received PEEK implants and eight received titanium implants. Data was acquired regarding quality of life, aesthetics, pain, demographics and complications. Quality of life was measured using the Glasgow Benefit Inventory (GBI). Additional questions were asked concerning pain, satisfaction and aesthetics. Results The mean total GBI-score was +26.1 (95%CI 16.8–35.4, p < 0.001). Headache complaints or pain in the operation site improved in 75.0% and 77.8% of these patients, respectively. In 8.0% an increase was seen with regard to both variables. Conclusion Reconstruction of skull bone defects with PEEK and titanium patient specific implants gave a statistically significant improvement in quality of life. Furthermore, it decreased pain and headaches and gave aesthetically good results.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>27916400</pmid><doi>10.1016/j.jcms.2016.10.016</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Cranioplasty Dentistry Esthetics Female Headache Humans Implants Ketones Male Middle Aged Pain, Postoperative - etiology Patient Satisfaction Polyetheretherketone Polyethylene Glycols Prostheses and Implants Quality of Life Reconstructive Surgical Procedures - methods Retrospective Studies Skull - surgery Surgery Titanium Young Adult |
| title | The therapeutic effect of patient-specific implants in cranioplasty |
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