Isolated Presence of Antibody to Hepatitis B Core Antigen in Injection Drug Users: Do They Need to Be Vaccinated?

In a study of 497 injection drug users who had isolated presence of antibody to hepatitis B core antigen (anti-HBc) at the time of enrollment, 404 (81%) retained this condition after a mean of 49 months of follow-up, during which time no new hepatitis B surface antigen marker was detected. These fin...

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Veröffentlicht in:	Clinical infectious diseases 2001-05, Vol.32 (10), p.e143-e144
Hauptverfasser:	Quaglio, Gianluca, Lugoboni, Fabio, Vento, Sandro, Lechi, Alessandro, Accordini, Augusto, Bossi, Carlo, Faccini, Marco, Mecenero, Valerio, Pani, Alessandro, Pantalena, Maurizio, Residori, Margherita, Mezzelani, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Female Hepatitis B - immunology Hepatitis B - prevention & control Hepatitis B Antibodies - blood Hepatitis B Core Antigens - immunology Hepatitis B Vaccines Humans Male Substance Abuse, Intravenous - complications Vaccination
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Zusammenfassung:	In a study of 497 injection drug users who had isolated presence of antibody to hepatitis B core antigen (anti-HBc) at the time of enrollment, 404 (81%) retained this condition after a mean of 49 months of follow-up, during which time no new hepatitis B surface antigen marker was detected. These findings support the hypothesis that patients with isolated presence of anti-HBc have strong resistance to reinfection and do not need vaccination.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/320162