Expanding specificity of class I restricted CD8+ T cells for viral epitopes following multiple inoculations of swine with a human adenovirus vectored foot-and-mouth disease virus (FMDV) vaccine

The immune response to the highly acute foot-and-mouth disease virus (FMDV) is routinely reported as a measure of serum antibody. However, a critical effector function of immune responses combating viral infection of mammals is the cytotoxic T lymphocyte (CTL) response mediated by virus specific CD8...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2016-11, Vol.181, p.59-67
Hauptverfasser:	Pedersen, Lasse E., Patch, Jared R., Kenney, Mary, Glabman, Raisa A., Nielsen, Morten, Jungersen, Gregers, Buus, Soren, Golde, William T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses, Human - genetics Animals CD8-Positive T-Lymphocytes - immunology Class I Cytotoxic T lymphocytes Epitopes Epitopes, T-Lymphocyte Foot-and-Mouth Disease Virus - immunology Genetic Vectors Humans MHC MHC tetramers SLA Swine T cell epitopes Vaccination - veterinary Vaccines, Synthetic - immunology Viral Vaccines - immunology
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