Serum AMH levels in healthy women from BRCA1/2 mutated families: are they reduced?

STUDY QUESTION Do BRCA1/2 mutation carriers have a compromised ovarian reserve compared to proven non-carriers, based on serum anti-Müllerian hormone (AMH) levels? SUMMARY ANSWER BRCA1/2 mutation carriers do not show a lower serum AMH level in comparison to proven non-carriers, after adjustment for...

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Veröffentlicht in:	Human reproduction (Oxford) 2016-11, Vol.31 (11), p.2651-2659
Hauptverfasser:	van Tilborg, Theodora C., Derks-Smeets, Inge A.P., Bos, Anna M.E., Oosterwijk, Jan C., van Golde, Ron J., de Die-Smulders, Christine E., van der Kolk, Lizet E., van Zelst-Stams, Wendy A.G., Velthuizen, Maria E., Hoek, Annemieke, Eijkemans, Marinus J.C., Laven, Joop S.E., Ausems, Margreet G.E.M., Broekmans, Frank J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Mullerian Hormone - blood BRCA1 Protein - genetics Cross-Sectional Studies Female Heterozygote Humans Prospective Studies Women's Health
Online-Zugang:	Volltext
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