Immunological evaluation of a DNA cocktail vaccine with co-delivery of calcium phosphate nanoparticles (CaPNs) against the Toxoplasma gondii RH strain in BALB/c mice

Many recent studies have been conducted to evaluate protective immunity mediated by DNA vaccines against toxoplasmosis. Cocktail DNA vaccines showed better immune responses compared to single vaccines. The objective of the current study was to evaluate the protective efficacy of rhomboid 4 (ROM4) an...

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Veröffentlicht in:	Parasitology research (1987) 2017-02, Vol.116 (2), p.609-616
Hauptverfasser:	Rahimi, Mohammad Taghi, Sarvi, Shahabeddin, Sharif, Mahdi, Abediankenari, Saeid, Ahmadpour, Ehsan, Valadan, Reza, Ramandie, Mahdi Fasihi, Hosseini, Seyed-Abdollah, Daryani, Ahmad
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adjuvants, Immunologic - genetics Animals Antibodies, Protozoan - immunology Biomedical and Life Sciences Biomedicine Calcium phosphate Calcium phosphates Calcium Phosphates - chemistry Deoxyribonucleic acid DNA DNA vaccines Female Humans Immune response (humoral) Immunity, Humoral Immunization Immunogenicity Immunoglobulin G - immunology Immunology Medical Microbiology Mice Mice, Inbred BALB C Microbiology Nanoparticles Nanoparticles - chemistry Original Paper Physiological aspects Protozoan Proteins - genetics Protozoan Vaccines - immunology Survival Toxoplasma Toxoplasma - genetics Toxoplasma - immunology Toxoplasmosis Toxoplasmosis, Animal - immunology Toxoplasmosis, Animal - parasitology Toxoplasmosis, Animal - prevention & control Vaccination Vaccines Vaccines, DNA - administration & dosage Vaccines, DNA - genetics Vaccines, DNA - immunology
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