Rational design of mimetic peptides based on aldo-ketoreductase enzyme as asymmetric organocatalysts in aldol reactions

Peptides as a kind of important chiral scaffold are broadly identified for their obvious advantages, diverse structures and accessibility. Based on promiscuous aldo-keto-reductase enzymes, several mimetic peptides were designed which were synthesized and tested as multifunctional organocatalysts in...

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Veröffentlicht in:	RSC advances 2014-01, Vol.4 (73), p.38859-38868
Hauptverfasser:	Bayat, Saadi, Tejo, Bimo A., Abdulmalek, Emilia, Salleh, Abu Bakar, Normi, Yahaya M., Abdul Rahman, Mohd Basyaruddin
Format:	Artikel
Sprache:	eng
Schlagworte:	Accessibility Aldehydes Asymmetry Catalysis Enzymes Peptides Scaffolds Synthesis (chemistry)
Online-Zugang:	Volltext
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