Differential Roles of Arrestin-2 Interaction with Clathrin and Adaptor Protein 2 in G Protein-coupled Receptor Trafficking

The non-visual arrestins, arrestin-2 and arrestin-3, play a critical role in regulating the signaling and trafficking of many G protein-coupled receptors (GPCRs). Molecular insight into the role of arrestins in GPCR trafficking has suggested that arrestin interaction with clathrin, Î² 2 -adaptin (th...

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Veröffentlicht in:	The Journal of biological chemistry 2002-08, Vol.277 (34), p.30760-30768
Hauptverfasser:	Kim, You-Me, Benovic, Jeffrey L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Protein Complex beta Subunits Amino Acid Sequence Animals Arrestins - chemistry Arrestins - physiology Binding Sites Biological Transport Cattle Clathrin - metabolism COS Cells Humans Membrane Proteins - metabolism Molecular Sequence Data Phosphoproteins - chemistry Phosphoproteins - physiology Receptors, Adrenergic, beta-2 - metabolism
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