Upfront boost Gamma Knife "leading-edge" radiosurgery to FLAIR MRI-defined tumor migration pathways in 174 patients with glioblastoma multiforme: a 15-year assessment of a novel therapy

OBJECTIVE Glioblastoma multiforme (GBM) is composed of cells that migrate through the brain along predictable white matter pathways. Targeting white matter pathways adjacent to, and leading away from, the original contrast-enhancing tumor site (termed leading-edge radiosurgery [LERS]) with single-fr...

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Veröffentlicht in:	Journal of neurosurgery 2016-12, Vol.125 (Suppl 1), p.40-49
Hauptverfasser:	Duma, Christopher M, Kim, Brian S, Chen, Peter V, Plunkett, Marianne E, Mackintosh, Ralph, Mathews, Marlon S, Casserly, Ryan M, Mendez, Gustavo A, Furman, Daniel J, Smith, Garrett, Oh, Nathan, Caraway, Chad A, Sanathara, Ami R, Dillman, Robert O, Riley, Azzurra-Sky, Weiland, David, Stemler, Lian, Cannell, Ruslana, Abrams, Daniela Alexandru, Smith, Alexa, Owen, Christopher M, Eisenberg, Burton, Brant-Zawadzki, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Brain Neoplasms - diagnostic imaging Brain Neoplasms - pathology Brain Neoplasms - radiotherapy Cell Movement Follow-Up Studies Glioblastoma - diagnostic imaging Glioblastoma - pathology Glioblastoma - radiotherapy Humans Magnetic Resonance Imaging - methods Middle Aged Radiosurgery - methods Retrospective Studies Time Factors Treatment Outcome Young Adult
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