The Integrative Weaning Index in Elderly ICU Subjects
With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide. We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 sub...
Gespeichert in:
| Veröffentlicht in: | Respiratory care 2017-03, Vol.62 (3), p.333-339 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 339 |
|---|---|
| container_issue | 3 |
| container_start_page | 333 |
| container_title | Respiratory care |
| container_volume | 62 |
| creator | Azeredo, Leandro M Nemer, Sérgio N Barbas, Carmen Sv Caldeira, Jefferson B Noé, Rosângela Guimarães, Bruno L Caldas, Célia P |
| description | With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.
We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those |
| doi_str_mv | 10.4187/respcare.04524 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1845247896</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A550390602</galeid><sourcerecordid>A550390602</sourcerecordid><originalsourceid>FETCH-LOGICAL-c499t-18613218dbc6b155f54cc2d2a5680c012ad9b2da6bd93bb810205cebb73d59743</originalsourceid><addsrcrecordid>eNptkctLAzEQxoMotj6uHmVBEC9b89xujlKqFgoeVDyGPGbbyHa3Jrti_3tTXyjIHMIMv28mHx9CJwSPOCnHlwHi2uoAI8wF5TtoSCRnOSsE30VDjCnOCaN8gA5ifE5twYXcRwM6LqUUjA2ReFhCNms6WATd-VfInkA3vlmkmYO3zDfZtHYQ6k02mzxm9715BtvFI7RX6TrC8dd7iB6vpw-T23x-dzObXM1zy6XsclIW6TopnbGFIUJUgltLHdWiKLHFhGonDXW6ME4yY0qS_issGDNmTsgxZ4fo4nPvOrQvPcROrXy0UNe6gbaPipRb18lMkdCzT3Sha1C-qdouaLvF1ZUQmElcYJqo0T9UKgcrb9sGKp_mfwTnvwRL0HW3jG3dd75t4r-bbWhjDFCpdfArHTaKYLWNSn1HpT6iSoLTL2-9WYH7wb-zYe-gYYyo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1845247896</pqid></control><display><type>article</type><title>The Integrative Weaning Index in Elderly ICU Subjects</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Azeredo, Leandro M ; Nemer, Sérgio N ; Barbas, Carmen Sv ; Caldeira, Jefferson B ; Noé, Rosângela ; Guimarães, Bruno L ; Caldas, Célia P</creator><creatorcontrib>Azeredo, Leandro M ; Nemer, Sérgio N ; Barbas, Carmen Sv ; Caldeira, Jefferson B ; Noé, Rosângela ; Guimarães, Bruno L ; Caldas, Célia P</creatorcontrib><description>With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.
We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those <70 y old were considered non-elderly. Besides the conventional weaning indexes, we evaluated the performance of the integrative weaning index (IWI). The probability of successful weaning was investigated using relative risk and logistic regression. The Hosmer-Lemeshow goodness-of-fit test was used to calibrate and the C statistic was calculated to evaluate the association between predicted probabilities and observed proportions in the logistic regression model.
Prevalence of successful weaning in the sample was 83.7%. There was no difference in mortality between elderly and non-elderly subjects (
= .16), in days of mechanical ventilation (
= .22) and days of weaning (
= .55). In elderly subjects, the IWI was the only respiratory variable associated with mechanical ventilation weaning in this population (
< .001).
The IWI was the independent variable found in weaning of elderly subjects that may contribute to the critical moment of this population in intensive care.</description><identifier>ISSN: 0020-1324</identifier><identifier>EISSN: 1943-3654</identifier><identifier>DOI: 10.4187/respcare.04524</identifier><identifier>PMID: 27899533</identifier><language>eng</language><publisher>United States: Daedalus Enterprises, Inc</publisher><subject>Aged ; Aged, 80 and over ; Critical Care - methods ; Elderly patients ; Female ; Geriatric Assessment - methods ; Humans ; Intensive Care Units ; Logistic Models ; Male ; Middle Aged ; Models, Statistical ; Mortality ; Nervous system diseases ; Risk ; Risk Assessment - methods ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Ventilator Weaning - methods ; Ventilator Weaning - statistics & numerical data</subject><ispartof>Respiratory care, 2017-03, Vol.62 (3), p.333-339</ispartof><rights>Copyright © 2017 by Daedalus Enterprises.</rights><rights>COPYRIGHT 2017 Daedalus Enterprises, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c499t-18613218dbc6b155f54cc2d2a5680c012ad9b2da6bd93bb810205cebb73d59743</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27899533$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Azeredo, Leandro M</creatorcontrib><creatorcontrib>Nemer, Sérgio N</creatorcontrib><creatorcontrib>Barbas, Carmen Sv</creatorcontrib><creatorcontrib>Caldeira, Jefferson B</creatorcontrib><creatorcontrib>Noé, Rosângela</creatorcontrib><creatorcontrib>Guimarães, Bruno L</creatorcontrib><creatorcontrib>Caldas, Célia P</creatorcontrib><title>The Integrative Weaning Index in Elderly ICU Subjects</title><title>Respiratory care</title><addtitle>Respir Care</addtitle><description>With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.
We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those <70 y old were considered non-elderly. Besides the conventional weaning indexes, we evaluated the performance of the integrative weaning index (IWI). The probability of successful weaning was investigated using relative risk and logistic regression. The Hosmer-Lemeshow goodness-of-fit test was used to calibrate and the C statistic was calculated to evaluate the association between predicted probabilities and observed proportions in the logistic regression model.
Prevalence of successful weaning in the sample was 83.7%. There was no difference in mortality between elderly and non-elderly subjects (
= .16), in days of mechanical ventilation (
= .22) and days of weaning (
= .55). In elderly subjects, the IWI was the only respiratory variable associated with mechanical ventilation weaning in this population (
< .001).
The IWI was the independent variable found in weaning of elderly subjects that may contribute to the critical moment of this population in intensive care.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Critical Care - methods</subject><subject>Elderly patients</subject><subject>Female</subject><subject>Geriatric Assessment - methods</subject><subject>Humans</subject><subject>Intensive Care Units</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Models, Statistical</subject><subject>Mortality</subject><subject>Nervous system diseases</subject><subject>Risk</subject><subject>Risk Assessment - methods</subject><subject>Severity of Illness Index</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Ventilator Weaning - methods</subject><subject>Ventilator Weaning - statistics & numerical data</subject><issn>0020-1324</issn><issn>1943-3654</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkctLAzEQxoMotj6uHmVBEC9b89xujlKqFgoeVDyGPGbbyHa3Jrti_3tTXyjIHMIMv28mHx9CJwSPOCnHlwHi2uoAI8wF5TtoSCRnOSsE30VDjCnOCaN8gA5ifE5twYXcRwM6LqUUjA2ReFhCNms6WATd-VfInkA3vlmkmYO3zDfZtHYQ6k02mzxm9715BtvFI7RX6TrC8dd7iB6vpw-T23x-dzObXM1zy6XsclIW6TopnbGFIUJUgltLHdWiKLHFhGonDXW6ME4yY0qS_issGDNmTsgxZ4fo4nPvOrQvPcROrXy0UNe6gbaPipRb18lMkdCzT3Sha1C-qdouaLvF1ZUQmElcYJqo0T9UKgcrb9sGKp_mfwTnvwRL0HW3jG3dd75t4r-bbWhjDFCpdfArHTaKYLWNSn1HpT6iSoLTL2-9WYH7wb-zYe-gYYyo</recordid><startdate>20170301</startdate><enddate>20170301</enddate><creator>Azeredo, Leandro M</creator><creator>Nemer, Sérgio N</creator><creator>Barbas, Carmen Sv</creator><creator>Caldeira, Jefferson B</creator><creator>Noé, Rosângela</creator><creator>Guimarães, Bruno L</creator><creator>Caldas, Célia P</creator><general>Daedalus Enterprises, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170301</creationdate><title>The Integrative Weaning Index in Elderly ICU Subjects</title><author>Azeredo, Leandro M ; Nemer, Sérgio N ; Barbas, Carmen Sv ; Caldeira, Jefferson B ; Noé, Rosângela ; Guimarães, Bruno L ; Caldas, Célia P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c499t-18613218dbc6b155f54cc2d2a5680c012ad9b2da6bd93bb810205cebb73d59743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Critical Care - methods</topic><topic>Elderly patients</topic><topic>Female</topic><topic>Geriatric Assessment - methods</topic><topic>Humans</topic><topic>Intensive Care Units</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Models, Statistical</topic><topic>Mortality</topic><topic>Nervous system diseases</topic><topic>Risk</topic><topic>Risk Assessment - methods</topic><topic>Severity of Illness Index</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ventilator Weaning - methods</topic><topic>Ventilator Weaning - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Azeredo, Leandro M</creatorcontrib><creatorcontrib>Nemer, Sérgio N</creatorcontrib><creatorcontrib>Barbas, Carmen Sv</creatorcontrib><creatorcontrib>Caldeira, Jefferson B</creatorcontrib><creatorcontrib>Noé, Rosângela</creatorcontrib><creatorcontrib>Guimarães, Bruno L</creatorcontrib><creatorcontrib>Caldas, Célia P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Respiratory care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Azeredo, Leandro M</au><au>Nemer, Sérgio N</au><au>Barbas, Carmen Sv</au><au>Caldeira, Jefferson B</au><au>Noé, Rosângela</au><au>Guimarães, Bruno L</au><au>Caldas, Célia P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Integrative Weaning Index in Elderly ICU Subjects</atitle><jtitle>Respiratory care</jtitle><addtitle>Respir Care</addtitle><date>2017-03-01</date><risdate>2017</risdate><volume>62</volume><issue>3</issue><spage>333</spage><epage>339</epage><pages>333-339</pages><issn>0020-1324</issn><eissn>1943-3654</eissn><abstract>With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.
We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those <70 y old were considered non-elderly. Besides the conventional weaning indexes, we evaluated the performance of the integrative weaning index (IWI). The probability of successful weaning was investigated using relative risk and logistic regression. The Hosmer-Lemeshow goodness-of-fit test was used to calibrate and the C statistic was calculated to evaluate the association between predicted probabilities and observed proportions in the logistic regression model.
Prevalence of successful weaning in the sample was 83.7%. There was no difference in mortality between elderly and non-elderly subjects (
= .16), in days of mechanical ventilation (
= .22) and days of weaning (
= .55). In elderly subjects, the IWI was the only respiratory variable associated with mechanical ventilation weaning in this population (
< .001).
The IWI was the independent variable found in weaning of elderly subjects that may contribute to the critical moment of this population in intensive care.</abstract><cop>United States</cop><pub>Daedalus Enterprises, Inc</pub><pmid>27899533</pmid><doi>10.4187/respcare.04524</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0020-1324 |
| ispartof | Respiratory care, 2017-03, Vol.62 (3), p.333-339 |
| issn | 0020-1324 1943-3654 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1845247896 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Aged Aged, 80 and over Critical Care - methods Elderly patients Female Geriatric Assessment - methods Humans Intensive Care Units Logistic Models Male Middle Aged Models, Statistical Mortality Nervous system diseases Risk Risk Assessment - methods Severity of Illness Index Time Factors Treatment Outcome Ventilator Weaning - methods Ventilator Weaning - statistics & numerical data |
| title | The Integrative Weaning Index in Elderly ICU Subjects |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T15%3A09%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Integrative%20Weaning%20Index%20in%20Elderly%20ICU%20Subjects&rft.jtitle=Respiratory%20care&rft.au=Azeredo,%20Leandro%20M&rft.date=2017-03-01&rft.volume=62&rft.issue=3&rft.spage=333&rft.epage=339&rft.pages=333-339&rft.issn=0020-1324&rft.eissn=1943-3654&rft_id=info:doi/10.4187/respcare.04524&rft_dat=%3Cgale_proqu%3EA550390602%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1845247896&rft_id=info:pmid/27899533&rft_galeid=A550390602&rfr_iscdi=true |