Micronuclei and sister chromatid exchanges induced by capsaicin in human lymphocytes

Capsaicin is the main pungent and irritating component of hot peppers (species Capsicum annuum and C. frutescens). Genotoxicity and carcinogenicity studies evaluating capsaicin effects are sparse and contradictory. In this study, we investigated the genotoxicity of capsaicin (10–200 μM) in human per...

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Veröffentlicht in:	Mutation research 2002-05, Vol.517 (1), p.39-46
Hauptverfasser:	Marques, S., Oliveira, N.G., Chaveca, T., Rueff, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Capsaicin Capsaicin - metabolism Capsaicin - toxicity Cells, Cultured Dose-Response Relationship, Drug Drug toxicity and drugs side effects treatment Female Human lymphocytes Humans Lymphocytes - drug effects Male Medical sciences Micronuclei Micronucleus Tests Middle Aged Miscellaneous (drug allergy, mutagens, teratogens...) Models, Chemical Pharmacology. Drug treatments Sister Chromatid Exchange Sister chromatid exchanges
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