Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values
Abstract Background Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleev...
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| Veröffentlicht in: | Surgery for obesity and related diseases 2017-03, Vol.13 (3), p.399-403 |
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| creator | Van Osdol, Andrew D., M.D Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S Borgert, Andrew J., Ph.D Kallies, Kara J., M.S Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S |
| description | Abstract Background Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleeve gastrectomy (LSG); with some indicating significantly greater reductions in total cholesterol and low-density lipoprotein (LDL) in LRYGB versus LSG, and others reporting no significant differences. Objectives To evaluate the postoperative lipid values after LRYGB versus LSG at a community hospital. Setting Integrated multispecialty health system with a community teaching hospital. Methods A retrospective review of our prospective database was completed to identify patients who underwent either LRYGB or LSG at our institution from 2001 through 2013. Lipid values available at 6–18 months postoperative were evaluated. Statistical analysis included χ2 and Wilcoxon rank-sum tests. A P value |
| doi_str_mv | 10.1016/j.soard.2016.09.031 |
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| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1844353194</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1550728916307304</els_id><sourcerecordid>1844353194</sourcerecordid><originalsourceid>FETCH-LOGICAL-c414t-6b073ba422bedb8a34587427069fde9ab620b1a9eb8817a6521e00897e9f6c823</originalsourceid><addsrcrecordid>eNqFkUtv1TAQhSMEog_4BUjISzYJfiW2FyChCtpKlZBaWLCyHGdS-ZLEwZNccf89Drew6KYrP-acOZpviuINoxWjrHm_qzC61FU8PypqKirYs-KUaaVLVQvxPN_rmpaKa3NSnCHuKBVNrfjL4oQrbaiQ_LS4vx5n5xcSezK42aWIPs7Bk9u4_i5hKn-QS4dLyj_tYXaIZA8JVyQ4AOyB3G9F8EscDyROZI64xBmSW0IuDmEOHdm7YQV8Vbzo3YDw-uE8L75_-fzt4qq8-Xp5ffHppvSSyaVsWqpE6yTnLXStdkLWWkmuaGP6DoxrG05b5gy0WjPlmpozoFQbBaZvvObivHh37Dun-CvnLnYM6GEY3ARxRcu0lKIWzMgsFUepz1Njgt7OKYwuHSyjdiNsd_YvYbsRttTYTDi73j4ErO0I3X_PP6RZ8OEogDzmPkCy6ANMHrqwkbJdDE8EfHzk90OYgnfDTzgA7uKapkzQMovcUnu3LXnbMWtEZkel-APPT6PF</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1844353194</pqid></control><display><type>article</type><title>Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Van Osdol, Andrew D., M.D ; Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S ; Borgert, Andrew J., Ph.D ; Kallies, Kara J., M.S ; Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</creator><creatorcontrib>Van Osdol, Andrew D., M.D ; Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S ; Borgert, Andrew J., Ph.D ; Kallies, Kara J., M.S ; Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</creatorcontrib><description>Abstract Background Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleeve gastrectomy (LSG); with some indicating significantly greater reductions in total cholesterol and low-density lipoprotein (LDL) in LRYGB versus LSG, and others reporting no significant differences. Objectives To evaluate the postoperative lipid values after LRYGB versus LSG at a community hospital. Setting Integrated multispecialty health system with a community teaching hospital. Methods A retrospective review of our prospective database was completed to identify patients who underwent either LRYGB or LSG at our institution from 2001 through 2013. Lipid values available at 6–18 months postoperative were evaluated. Statistical analysis included χ2 and Wilcoxon rank-sum tests. A P value<.05 was considered significant. Results There were 1326 and 121 patients who underwent LRYGB and LSG during the study period, respectively. Of these patients, 644 LRYGB and 67 LSG patients had pre- and postoperative lipid values available and included in the final analysis. Postoperative mean total cholesterol and LDL values were significantly lower in LYRGB versus LSG patients. Postoperatively, 10% and 30% of LRYGB and LSG patients had a total cholesterol values≥200 mg/dL ( P <.001); 4% and 24% had LDL values≥130 mg/dL ( P <.001); and 8% and 9% had triglyceride levels>130 mg/dL ( P = .68), respectively. HDL values were within the recommended range in 52% and 57% of LRYGB and LSG patients, respectively ( P = .64). Conclusion Patients who underwent LRYGB had a greater postoperative reduction in total cholesterol, LDL, and triglycerides. LRYGB may be the more appropriate bariatric procedure for patients with significant preoperative hypercholesterolemia.</description><identifier>ISSN: 1550-7289</identifier><identifier>EISSN: 1878-7533</identifier><identifier>DOI: 10.1016/j.soard.2016.09.031</identifier><identifier>PMID: 27890342</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Bariatric surgery ; Cholesterol ; Cholesterol, HDL - metabolism ; Cholesterol, LDL - metabolism ; Dyslipidemia ; Female ; Gastrectomy - methods ; Gastric Bypass - methods ; Gastroenterology and Hepatology ; Humans ; Hypercholesterolemia - blood ; Hypercholesterolemia - complications ; Laparoscopy - methods ; Lipids ; Male ; Metabolic surgery ; Middle Aged ; Obesity, Morbid - blood ; Obesity, Morbid - complications ; Obesity, Morbid - surgery ; Postoperative Care ; Postoperative outcomes ; Prospective Studies ; Retrospective Studies ; Roux-en-Y gastric bypass ; Sleeve gastrectomy ; Surgery ; Triglycerides - metabolism</subject><ispartof>Surgery for obesity and related diseases, 2017-03, Vol.13 (3), p.399-403</ispartof><rights>American Society for Bariatric Surgery</rights><rights>2017 American Society for Bariatric Surgery</rights><rights>Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-6b073ba422bedb8a34587427069fde9ab620b1a9eb8817a6521e00897e9f6c823</citedby><cites>FETCH-LOGICAL-c414t-6b073ba422bedb8a34587427069fde9ab620b1a9eb8817a6521e00897e9f6c823</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1550728916307304$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27890342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Van Osdol, Andrew D., M.D</creatorcontrib><creatorcontrib>Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S</creatorcontrib><creatorcontrib>Borgert, Andrew J., Ph.D</creatorcontrib><creatorcontrib>Kallies, Kara J., M.S</creatorcontrib><creatorcontrib>Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</creatorcontrib><title>Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values</title><title>Surgery for obesity and related diseases</title><addtitle>Surg Obes Relat Dis</addtitle><description>Abstract Background Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleeve gastrectomy (LSG); with some indicating significantly greater reductions in total cholesterol and low-density lipoprotein (LDL) in LRYGB versus LSG, and others reporting no significant differences. Objectives To evaluate the postoperative lipid values after LRYGB versus LSG at a community hospital. Setting Integrated multispecialty health system with a community teaching hospital. Methods A retrospective review of our prospective database was completed to identify patients who underwent either LRYGB or LSG at our institution from 2001 through 2013. Lipid values available at 6–18 months postoperative were evaluated. Statistical analysis included χ2 and Wilcoxon rank-sum tests. A P value<.05 was considered significant. Results There were 1326 and 121 patients who underwent LRYGB and LSG during the study period, respectively. Of these patients, 644 LRYGB and 67 LSG patients had pre- and postoperative lipid values available and included in the final analysis. Postoperative mean total cholesterol and LDL values were significantly lower in LYRGB versus LSG patients. Postoperatively, 10% and 30% of LRYGB and LSG patients had a total cholesterol values≥200 mg/dL ( P <.001); 4% and 24% had LDL values≥130 mg/dL ( P <.001); and 8% and 9% had triglyceride levels>130 mg/dL ( P = .68), respectively. HDL values were within the recommended range in 52% and 57% of LRYGB and LSG patients, respectively ( P = .64). Conclusion Patients who underwent LRYGB had a greater postoperative reduction in total cholesterol, LDL, and triglycerides. LRYGB may be the more appropriate bariatric procedure for patients with significant preoperative hypercholesterolemia.</description><subject>Bariatric surgery</subject><subject>Cholesterol</subject><subject>Cholesterol, HDL - metabolism</subject><subject>Cholesterol, LDL - metabolism</subject><subject>Dyslipidemia</subject><subject>Female</subject><subject>Gastrectomy - methods</subject><subject>Gastric Bypass - methods</subject><subject>Gastroenterology and Hepatology</subject><subject>Humans</subject><subject>Hypercholesterolemia - blood</subject><subject>Hypercholesterolemia - complications</subject><subject>Laparoscopy - methods</subject><subject>Lipids</subject><subject>Male</subject><subject>Metabolic surgery</subject><subject>Middle Aged</subject><subject>Obesity, Morbid - blood</subject><subject>Obesity, Morbid - complications</subject><subject>Obesity, Morbid - surgery</subject><subject>Postoperative Care</subject><subject>Postoperative outcomes</subject><subject>Prospective Studies</subject><subject>Retrospective Studies</subject><subject>Roux-en-Y gastric bypass</subject><subject>Sleeve gastrectomy</subject><subject>Surgery</subject><subject>Triglycerides - metabolism</subject><issn>1550-7289</issn><issn>1878-7533</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUtv1TAQhSMEog_4BUjISzYJfiW2FyChCtpKlZBaWLCyHGdS-ZLEwZNccf89Drew6KYrP-acOZpviuINoxWjrHm_qzC61FU8PypqKirYs-KUaaVLVQvxPN_rmpaKa3NSnCHuKBVNrfjL4oQrbaiQ_LS4vx5n5xcSezK42aWIPs7Bk9u4_i5hKn-QS4dLyj_tYXaIZA8JVyQ4AOyB3G9F8EscDyROZI64xBmSW0IuDmEOHdm7YQV8Vbzo3YDw-uE8L75_-fzt4qq8-Xp5ffHppvSSyaVsWqpE6yTnLXStdkLWWkmuaGP6DoxrG05b5gy0WjPlmpozoFQbBaZvvObivHh37Dun-CvnLnYM6GEY3ARxRcu0lKIWzMgsFUepz1Njgt7OKYwuHSyjdiNsd_YvYbsRttTYTDi73j4ErO0I3X_PP6RZ8OEogDzmPkCy6ANMHrqwkbJdDE8EfHzk90OYgnfDTzgA7uKapkzQMovcUnu3LXnbMWtEZkel-APPT6PF</recordid><startdate>20170301</startdate><enddate>20170301</enddate><creator>Van Osdol, Andrew D., M.D</creator><creator>Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S</creator><creator>Borgert, Andrew J., Ph.D</creator><creator>Kallies, Kara J., M.S</creator><creator>Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170301</creationdate><title>Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values</title><author>Van Osdol, Andrew D., M.D ; Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S ; Borgert, Andrew J., Ph.D ; Kallies, Kara J., M.S ; Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-6b073ba422bedb8a34587427069fde9ab620b1a9eb8817a6521e00897e9f6c823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Bariatric surgery</topic><topic>Cholesterol</topic><topic>Cholesterol, HDL - metabolism</topic><topic>Cholesterol, LDL - metabolism</topic><topic>Dyslipidemia</topic><topic>Female</topic><topic>Gastrectomy - methods</topic><topic>Gastric Bypass - methods</topic><topic>Gastroenterology and Hepatology</topic><topic>Humans</topic><topic>Hypercholesterolemia - blood</topic><topic>Hypercholesterolemia - complications</topic><topic>Laparoscopy - methods</topic><topic>Lipids</topic><topic>Male</topic><topic>Metabolic surgery</topic><topic>Middle Aged</topic><topic>Obesity, Morbid - blood</topic><topic>Obesity, Morbid - complications</topic><topic>Obesity, Morbid - surgery</topic><topic>Postoperative Care</topic><topic>Postoperative outcomes</topic><topic>Prospective Studies</topic><topic>Retrospective Studies</topic><topic>Roux-en-Y gastric bypass</topic><topic>Sleeve gastrectomy</topic><topic>Surgery</topic><topic>Triglycerides - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Van Osdol, Andrew D., M.D</creatorcontrib><creatorcontrib>Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S</creatorcontrib><creatorcontrib>Borgert, Andrew J., Ph.D</creatorcontrib><creatorcontrib>Kallies, Kara J., M.S</creatorcontrib><creatorcontrib>Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery for obesity and related diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Van Osdol, Andrew D., M.D</au><au>Grover, Brandon T., D.O., F.A.C.S., F.A.S.M.B.S</au><au>Borgert, Andrew J., Ph.D</au><au>Kallies, Kara J., M.S</au><au>Kothari, Shanu N., M.D., F.A.C.S., F.A.S.M.B.S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values</atitle><jtitle>Surgery for obesity and related diseases</jtitle><addtitle>Surg Obes Relat Dis</addtitle><date>2017-03-01</date><risdate>2017</risdate><volume>13</volume><issue>3</issue><spage>399</spage><epage>403</epage><pages>399-403</pages><issn>1550-7289</issn><eissn>1878-7533</eissn><abstract>Abstract Background Metabolic surgery has been shown to significantly improve many obesity-related co-morbidities, including dyslipidemia. The literature has produced mixed results comparing postoperative lipid values after laparoscopic Roux-en-Y gastric bypass (LRYGB) compared to laparoscopic sleeve gastrectomy (LSG); with some indicating significantly greater reductions in total cholesterol and low-density lipoprotein (LDL) in LRYGB versus LSG, and others reporting no significant differences. Objectives To evaluate the postoperative lipid values after LRYGB versus LSG at a community hospital. Setting Integrated multispecialty health system with a community teaching hospital. Methods A retrospective review of our prospective database was completed to identify patients who underwent either LRYGB or LSG at our institution from 2001 through 2013. Lipid values available at 6–18 months postoperative were evaluated. Statistical analysis included χ2 and Wilcoxon rank-sum tests. A P value<.05 was considered significant. Results There were 1326 and 121 patients who underwent LRYGB and LSG during the study period, respectively. Of these patients, 644 LRYGB and 67 LSG patients had pre- and postoperative lipid values available and included in the final analysis. Postoperative mean total cholesterol and LDL values were significantly lower in LYRGB versus LSG patients. Postoperatively, 10% and 30% of LRYGB and LSG patients had a total cholesterol values≥200 mg/dL ( P <.001); 4% and 24% had LDL values≥130 mg/dL ( P <.001); and 8% and 9% had triglyceride levels>130 mg/dL ( P = .68), respectively. HDL values were within the recommended range in 52% and 57% of LRYGB and LSG patients, respectively ( P = .64). Conclusion Patients who underwent LRYGB had a greater postoperative reduction in total cholesterol, LDL, and triglycerides. LRYGB may be the more appropriate bariatric procedure for patients with significant preoperative hypercholesterolemia.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27890342</pmid><doi>10.1016/j.soard.2016.09.031</doi><tpages>5</tpages></addata></record> |
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| subjects | Bariatric surgery Cholesterol Cholesterol, HDL - metabolism Cholesterol, LDL - metabolism Dyslipidemia Female Gastrectomy - methods Gastric Bypass - methods Gastroenterology and Hepatology Humans Hypercholesterolemia - blood Hypercholesterolemia - complications Laparoscopy - methods Lipids Male Metabolic surgery Middle Aged Obesity, Morbid - blood Obesity, Morbid - complications Obesity, Morbid - surgery Postoperative Care Postoperative outcomes Prospective Studies Retrospective Studies Roux-en-Y gastric bypass Sleeve gastrectomy Surgery Triglycerides - metabolism |
| title | Impact of laparoscopic Roux-en-Y Gastric bypass versus sleeve gastrectomy on postoperative lipid values |
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