Anti-tumor and immunomodulatory activities induced by an alkali-extracted polysaccharide BCAP-1 from Bupleurum chinense via NF-κB signaling pathway

•BCAP-1, an alkali-extracted polysaccharide from Bupleurum chinense, inhibited tumor growth in vivo and increased TNF-α in serum.•BCAP-1 treatment induced the phosphorylation of p65 and decreased the expression of IκB in peritoneal macrophages.•BCAP-1 activates macrophages through NF-κB signaling.•T...

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