Deterioration of Vestibular Cells in Labyrinthitis
Objective: To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells. Methods: We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and l...
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| Veröffentlicht in: | Annals of otology, rhinology & laryngology rhinology & laryngology, 2017-02, Vol.126 (2), p.89-95 |
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| container_title | Annals of otology, rhinology & laryngology |
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| creator | Kaya, Serdar Schachern, Patricia A. Tsuprun, Vladimir Paparella, Michael M. Cureoglu, Sebahattin |
| description | Objective:
To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells.
Methods:
We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans, then compared them with age-matched control groups without labyrinthitis. We evaluated the density of type I and II vestibular hair cells, dark cells, and transitional cells in the peripheral sensorial organs.
Results:
The mean density of type I vestibular hair cells in the maculae of the saccule significantly differed between the serous labyrinthitis group and its control group. The loss of type I and II vestibular hair cells in all of the peripheral sensorial organs was significantly higher in the suppurative labyrinthitis group than in its control group. The mean density of dark cells in the lateral and posterior semicircular canals was significantly lower in the suppurative labyrinthitis group than in its control group. The mean density of type I and II vestibular hair cells, dark cells, and transitional cells was significantly lower in the labyrinthitis ossificans group than in its control group.
Conclusion:
The loss of vestibular hair cells and degenerative changes in dark cells and transitional cells could affect vestibular function in patients with labyrinthitis. |
| doi_str_mv | 10.1177/0003489416675356 |
| format | Article |
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To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells.
Methods:
We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans, then compared them with age-matched control groups without labyrinthitis. We evaluated the density of type I and II vestibular hair cells, dark cells, and transitional cells in the peripheral sensorial organs.
Results:
The mean density of type I vestibular hair cells in the maculae of the saccule significantly differed between the serous labyrinthitis group and its control group. The loss of type I and II vestibular hair cells in all of the peripheral sensorial organs was significantly higher in the suppurative labyrinthitis group than in its control group. The mean density of dark cells in the lateral and posterior semicircular canals was significantly lower in the suppurative labyrinthitis group than in its control group. The mean density of type I and II vestibular hair cells, dark cells, and transitional cells was significantly lower in the labyrinthitis ossificans group than in its control group.
Conclusion:
The loss of vestibular hair cells and degenerative changes in dark cells and transitional cells could affect vestibular function in patients with labyrinthitis.</description><identifier>ISSN: 0003-4894</identifier><identifier>EISSN: 1943-572X</identifier><identifier>DOI: 10.1177/0003489416675356</identifier><identifier>PMID: 27881797</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Acoustic Maculae - pathology ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Cadaver ; Cell Count ; Child ; Child, Preschool ; Female ; Hair Cells, Vestibular - pathology ; Humans ; Infant ; Labyrinthitis - classification ; Labyrinthitis - pathology ; Male ; Middle Aged ; Saccule and Utricle - pathology ; Temporal Bone - pathology ; Vestibule, Labyrinth - pathology ; Young Adult</subject><ispartof>Annals of otology, rhinology & laryngology, 2017-02, Vol.126 (2), p.89-95</ispartof><rights>The Author(s) 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-824f215e1ca81956e6a0162a89e2708f9e25026de516299c65dca71f398321173</citedby><cites>FETCH-LOGICAL-c337t-824f215e1ca81956e6a0162a89e2708f9e25026de516299c65dca71f398321173</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0003489416675356$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0003489416675356$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>315,781,785,21821,27926,27927,43623,43624</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27881797$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kaya, Serdar</creatorcontrib><creatorcontrib>Schachern, Patricia A.</creatorcontrib><creatorcontrib>Tsuprun, Vladimir</creatorcontrib><creatorcontrib>Paparella, Michael M.</creatorcontrib><creatorcontrib>Cureoglu, Sebahattin</creatorcontrib><title>Deterioration of Vestibular Cells in Labyrinthitis</title><title>Annals of otology, rhinology & laryngology</title><addtitle>Ann Otol Rhinol Laryngol</addtitle><description>Objective:
To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells.
Methods:
We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans, then compared them with age-matched control groups without labyrinthitis. We evaluated the density of type I and II vestibular hair cells, dark cells, and transitional cells in the peripheral sensorial organs.
Results:
The mean density of type I vestibular hair cells in the maculae of the saccule significantly differed between the serous labyrinthitis group and its control group. The loss of type I and II vestibular hair cells in all of the peripheral sensorial organs was significantly higher in the suppurative labyrinthitis group than in its control group. The mean density of dark cells in the lateral and posterior semicircular canals was significantly lower in the suppurative labyrinthitis group than in its control group. The mean density of type I and II vestibular hair cells, dark cells, and transitional cells was significantly lower in the labyrinthitis ossificans group than in its control group.
Conclusion:
The loss of vestibular hair cells and degenerative changes in dark cells and transitional cells could affect vestibular function in patients with labyrinthitis.</description><subject>Acoustic Maculae - pathology</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cadaver</subject><subject>Cell Count</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hair Cells, Vestibular - pathology</subject><subject>Humans</subject><subject>Infant</subject><subject>Labyrinthitis - classification</subject><subject>Labyrinthitis - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Saccule and Utricle - pathology</subject><subject>Temporal Bone - pathology</subject><subject>Vestibule, Labyrinth - pathology</subject><subject>Young Adult</subject><issn>0003-4894</issn><issn>1943-572X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1ULtOAzEQtBCIhEBPha6kOfDa51eJwlOKRAOIznIue-Docg72XZG_x1ECBRLVandmRzNDyDnQKwClrimlvNKmAimV4EIekDGYipdCsfdDMt7C5RYfkZOUlnmtBGXHZMSU1qCMGhN2iz1GH6LrfeiK0BRvmHo_H1oXiym2bSp8V8zcfBN913_63qdTctS4NuHZfk7I6_3dy_SxnD0_PE1vZmXNuepLzaqGgUConQYjJEpHQTKnDTJFdZNHNiMXKPLVmFqKRe0UNNxoznI6PiGXO911DF9DdmVXPtXZkuswDMmCrriRhkmdqXRHrWNIKWJj19GvXNxYoHbblP3bVH652KsP8xUufh9-qsmEckdI7gPtMgyxy2n_F_wG2YpuEQ</recordid><startdate>201702</startdate><enddate>201702</enddate><creator>Kaya, Serdar</creator><creator>Schachern, Patricia A.</creator><creator>Tsuprun, Vladimir</creator><creator>Paparella, Michael M.</creator><creator>Cureoglu, Sebahattin</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201702</creationdate><title>Deterioration of Vestibular Cells in Labyrinthitis</title><author>Kaya, Serdar ; Schachern, Patricia A. ; Tsuprun, Vladimir ; Paparella, Michael M. ; Cureoglu, Sebahattin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-824f215e1ca81956e6a0162a89e2708f9e25026de516299c65dca71f398321173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Acoustic Maculae - pathology</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cadaver</topic><topic>Cell Count</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Hair Cells, Vestibular - pathology</topic><topic>Humans</topic><topic>Infant</topic><topic>Labyrinthitis - classification</topic><topic>Labyrinthitis - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Saccule and Utricle - pathology</topic><topic>Temporal Bone - pathology</topic><topic>Vestibule, Labyrinth - pathology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaya, Serdar</creatorcontrib><creatorcontrib>Schachern, Patricia A.</creatorcontrib><creatorcontrib>Tsuprun, Vladimir</creatorcontrib><creatorcontrib>Paparella, Michael M.</creatorcontrib><creatorcontrib>Cureoglu, Sebahattin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of otology, rhinology & laryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaya, Serdar</au><au>Schachern, Patricia A.</au><au>Tsuprun, Vladimir</au><au>Paparella, Michael M.</au><au>Cureoglu, Sebahattin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Deterioration of Vestibular Cells in Labyrinthitis</atitle><jtitle>Annals of otology, rhinology & laryngology</jtitle><addtitle>Ann Otol Rhinol Laryngol</addtitle><date>2017-02</date><risdate>2017</risdate><volume>126</volume><issue>2</issue><spage>89</spage><epage>95</epage><pages>89-95</pages><issn>0003-4894</issn><eissn>1943-572X</eissn><abstract>Objective:
To quantitatively assess the effect of serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans on vestibular hair cells, dark cells, and transitional cells.
Methods:
We examined human temporal bone specimens with serous labyrinthitis, suppurative labyrinthitis, and labyrinthitis ossificans, then compared them with age-matched control groups without labyrinthitis. We evaluated the density of type I and II vestibular hair cells, dark cells, and transitional cells in the peripheral sensorial organs.
Results:
The mean density of type I vestibular hair cells in the maculae of the saccule significantly differed between the serous labyrinthitis group and its control group. The loss of type I and II vestibular hair cells in all of the peripheral sensorial organs was significantly higher in the suppurative labyrinthitis group than in its control group. The mean density of dark cells in the lateral and posterior semicircular canals was significantly lower in the suppurative labyrinthitis group than in its control group. The mean density of type I and II vestibular hair cells, dark cells, and transitional cells was significantly lower in the labyrinthitis ossificans group than in its control group.
Conclusion:
The loss of vestibular hair cells and degenerative changes in dark cells and transitional cells could affect vestibular function in patients with labyrinthitis.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>27881797</pmid><doi>10.1177/0003489416675356</doi><tpages>7</tpages></addata></record> |
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| subjects | Acoustic Maculae - pathology Adolescent Adult Aged Aged, 80 and over Cadaver Cell Count Child Child, Preschool Female Hair Cells, Vestibular - pathology Humans Infant Labyrinthitis - classification Labyrinthitis - pathology Male Middle Aged Saccule and Utricle - pathology Temporal Bone - pathology Vestibule, Labyrinth - pathology Young Adult |
| title | Deterioration of Vestibular Cells in Labyrinthitis |
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