Macrophage-derived exosomes induce inflammatory factors in endothelial cells under hypertensive conditions

Hypertension is one of the most important cardiovascular risk factors and results in macrophage infiltration of blood vessels. However, how macrophages coordinate inflammatory responses with endothelial cells (ECs) remains unclear. In this study, we investigated whether exosomes upregulate the expre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hypertension research 2017-04, Vol.40 (4), p.353-360
Hauptverfasser:	Osada-Oka, Mayuko, Shiota, Masayuki, Izumi, Yasukatsu, Nishiyama, Masaki, Tanaka, Masako, Yamaguchi, Takehiro, Sakurai, Emi, Miura, Katsuyuki, Iwao, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Animals Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Endocrine system Endothelial Cells - metabolism Exosomes - metabolism Hypertension Hypertension - chemically induced Hypertension - metabolism Inflammation Inflammation - metabolism Intercellular Adhesion Molecule-1 - metabolism Macrophages - metabolism Male Pathogenesis Plasminogen Activator Inhibitor 1 - metabolism Rats Rats, Wistar Rodents
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!