Hypolipidemic Effect of Mannan in Mice with Acute Lipemia Induced by Poloxamer 407

We studied biological effects of mannan, a polysaccharide immunomodulator from C. albicans , that interacts with mannose receptor in vivo . It is shown that preliminary administration of mannan (5 times in a dose of 50 mg/kg or 2 times in a dose of 100 mg/kg) to mice with acute lipemia induced by li...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2016-11, Vol.162 (1), p.18-22
Hauptverfasser:	Goncharova, N. V., Khrapova, M. V., Pupyshev, A. B., Korolenko, E. Ts, Nešéáková, Z., Korolenko, T. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antilipemic agents Biomedical and Life Sciences Biomedicine Candida albicans - chemistry Cell activation Cell Biology Cholesterol Cholesterol, HDL - blood Cholesterol, LDL - blood Fungal Polysaccharides - isolation & purification Fungal Polysaccharides - pharmacology Hexosaminidases - blood Hyperlipidemias - blood Hyperlipidemias - chemically induced Hyperlipidemias - drug therapy Hyperlipidemias - pathology Injections, Intraperitoneal Internal Medicine Intracellular Membranes - chemistry Intracellular Membranes - drug effects Laboratory Medicine Lipase Lipopolysaccharides Liver Liver - drug effects Liver - metabolism Low density lipoprotein Low density lipoproteins Lysosomes - chemistry Lysosomes - drug effects Macrophage Activation - drug effects Macrophages Macrophages - cytology Macrophages - drug effects Macrophages - metabolism Male Mannan Mannans - isolation & purification Mannans - pharmacology Mannose Mice Mice, Inbred CBA Monosaccharides Pathology Poloxamer - pharmacology Polysaccharides Rodents Triglycerides Triglycerides - blood
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