Exercise Attenuates High-Fat Diet–induced Disease Progression in 3xTg-AD Mice

PURPOSELittle is known regarding the therapeutic role of exercise against the risk of a high-fat diet (HFD) for Alzheimerʼs disease (AD) and AD-like cognitive deficits. This study aimed to investigate the therapeutic effect of treadmill running against HFD-induced progression in AD neuropathology an...

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Veröffentlicht in:	Medicine and science in sports and exercise 2017-04, Vol.49 (4), p.676-686
Hauptverfasser:	KIM, DONGHYUN, CHO, JINKYUNG, LEE, INHWAN, JIN, YOUNGYUN, KANG, HYUNSIK
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer Disease - physiopathology Amyloid - metabolism Animals Apoptosis Blood Glucose - metabolism Brain - metabolism Brain-Derived Neurotrophic Factor Cholesterol - blood Diet, High-Fat Disease Models, Animal Disease Progression Down-Regulation Insulin - blood Insulin - metabolism Male Mice, Transgenic Neuronal Plasticity Physical Conditioning, Animal - physiology Running - physiology tau Proteins - metabolism Triglycerides - blood
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