Enhancing tablet disintegration characteristics of a highly water-soluble high-drug-loading formulation by granulation process

The objective of this study was to improve the disintegration and dissolution characteristics of a highly water-soluble tablet matrix by altering the manufacturing process. A high disintegration time along with high dependence of the disintegration time on tablet hardness was observed for a high dru...

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Veröffentlicht in:	Pharmaceutical development and technology 2018-07, Vol.23 (6), p.587-595
Hauptverfasser:	Pandey, Preetanshu, Levins, Christopher, Pafiakis, Steve, Zacour, Brian, Bindra, Dilbir S, Trinh, Jade, Buckley, David, Gour, Shruti, Sharif, Shasad, Stamato, Howard
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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