Toxins ‘R’ Us: more pharmacological tools from nature's superstore

Conus venoms from marine cone snails continue to provide novel bioactive components. Two new classes of conopeptide specifically block α 1-adrenoceptors (ρ-conopeptide) and noradrenaline transporters (χ-conopeptides). Both classes are small peptides with two disulfide bonds. ρ-Conopeptide is structu...

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Veröffentlicht in:	Trends in pharmacological sciences (Regular ed.) 2002-05, Vol.23 (5), p.201-203
1. Verfasser:	Harvey, Alan L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-1 Receptor Antagonists Amino Acid Sequence Animals Conotoxins - classification Conotoxins - pharmacology Humans Molecular Sequence Data Norepinephrine Plasma Membrane Transport Proteins Symporters - antagonists & inhibitors
Online-Zugang:	Volltext
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