Inhibition on the growth of human MDA-MB-231 breast cancer cells in vitro and tumor growth in a mouse xenograft model by Se-containing polysaccharides from Pyracantha fortuneana

Abstract Breast cancer is the second cause of cancer-related death among Women. Current therapies for breast cancer have adverse side-effects. Selenium(Se)-containing polysaccharides have multiple health benefits to humans . Pyracantha fortuneana ( P. fortuneana ) contains rich Se polysaccharides. W...

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Veröffentlicht in:	Nutrition research (New York, N.Y.) N.Y.), 2016-11, Vol.36 (11), p.1243-1254
Hauptverfasser:	Yuan, Chengfu, Wang, Changdong, Wang, Junjie, Kumar, Vikas, Anwar, Firoz, Xiao, Fangxiang, Mushtaq, Gohar, Liu, Yufei, Kamal, Mohammad Amjad, Yuan, Ding
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Breast cancer Breast Neoplasms - therapy Caspase 3 - genetics Caspase 3 - metabolism Caspase 9 - genetics Caspase 9 - metabolism Cell Cycle - drug effects Cell Line, Tumor Cell Proliferation - drug effects Disease Models, Animal Doxorubicin - pharmacology Female Gastroenterology and Hepatology Humans Mice Mice, Inbred BALB C Mice, Nude Nude mice Plant Extracts - pharmacology Polysaccharides - chemistry Polysaccharides - pharmacology Pyracantha - chemistry Pyracantha fortuneana Selenium - pharmacology Selenium-enriched polysaccharides Sensitivity and Specificity Xenograft Model Antitumor Assays
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