Metformin exposure and disseminated disease in patients with colorectal cancer

Abstract Background Preclinical evidence suggests a role for metformin in inhibiting tumour dissemination and metastasis. Previous studies have identified associations between metformin exposure and improved colorectal cancer survival. This study aimed to examine associations between metformin expos...

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Veröffentlicht in:	Cancer epidemiology 2014-02, Vol.38 (1), p.79-84
Hauptverfasser:	Spillane, Susan, Bennett, Kathleen, Sharp, Linda, Barron, Thomas I
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Analysis. Health state Biguanides Biological and medical sciences Cancer Cancer therapies Colorectal cancer Colorectal neoplasms Colorectal Neoplasms - epidemiology Colorectal Neoplasms - pathology Databases, Factual Diabetes Diabetes mellitus Dose-Response Relationship, Drug Drug dosages Epidemiology Female General aspects Hematology, Oncology and Palliative Medicine Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - pharmacology Internal Medicine Ireland Logistic Models Lymph nodes Lymphatic Metastasis - prevention & control Male Medical diagnosis Medical prognosis Medical sciences Metastasis Metformin Metformin - administration & dosage Metformin - pharmacology Morphology Multivariate Analysis Neoplasm metastasis Neoplasm Metastasis - prevention & control Pharmacoepidemiology Pharmacy Public health. Hygiene Public health. Hygiene-occupational medicine Skin cancer Studies Tumors Type 2
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