Feasibility of three-dimensional ultrashort echo time magnetic resonance imaging at 1.5 T for the diagnosis of skull fractures

Objectives To investigate the feasibility of ultrashort echo time (UTE) magnetic resonance imaging (MRI) for the diagnosis of skull fractures. Methods The skull fracture models of ten Bama pigs and 364 patients with craniocerebral trauma were subjected to computed tomography (CT), UTE and convention...

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Veröffentlicht in:European radiology 2016-01, Vol.26 (1), p.138-146
Hauptverfasser: Wu, Hao, Zhong, Yu-min, Nie, Quan-min, Chen, Wei-bo, Guo, Lie-mei, Yang, Xi, Zhang, Hong, Lin, Yi, Xu, Jian-rong, Dai, Yong-ming, Zhu, Ming
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container_end_page 146
container_issue 1
container_start_page 138
container_title European radiology
container_volume 26
creator Wu, Hao
Zhong, Yu-min
Nie, Quan-min
Chen, Wei-bo
Guo, Lie-mei
Yang, Xi
Zhang, Hong
Lin, Yi
Xu, Jian-rong
Dai, Yong-ming
Zhu, Ming
description Objectives To investigate the feasibility of ultrashort echo time (UTE) magnetic resonance imaging (MRI) for the diagnosis of skull fractures. Methods The skull fracture models of ten Bama pigs and 364 patients with craniocerebral trauma were subjected to computed tomography (CT), UTE and conventional MRI sequences. The accuracy of UTE imaging in skull fracture diagnosis was analysed using receiver operating characteristic (ROC) curve analysis, McNemar’s test and Kappa values. Differences among CT, UTE imaging and anatomical measurement (AM) values for linear fractures (LFs) and depressed fractures (DFs) were compared using one-way ANOVA and a paired-samples t-test. Results UTE imaging clearly demonstrated skull structures and fractures. The accuracy, validity and reliability of UTE MRI were excellent, with no significant differences between expert readings ( P  > 0.05; Kappa, 0.899). The values obtained for 42 LFs and 13 DFs in the ten specimens were not significantly different among CT, UTE MRI and AMs, while those obtained for 55 LFs and ten DFs in 44 patients were not significantly different between CT and UTE MRI ( P  > 0.05). Conclusions UTE MRI sequences are feasible for the evaluation of skull structures and fractures, with no radiation exposure, particularly for paediatric and pregnant patients. Key Points • Despite ionising radiation, CT is standard for skull fracture assessment . • Conventional MRI cannot depict skull structures . • 3D-UTE sequences clearly demonstrate skull structures and fractures . • UTE plus conventional MRI are superior to CT in craniocerebral trauma assessment . • Paediatric and pregnant patients will benefit from this imaging modality .
doi_str_mv 10.1007/s00330-015-3804-2
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Methods The skull fracture models of ten Bama pigs and 364 patients with craniocerebral trauma were subjected to computed tomography (CT), UTE and conventional MRI sequences. The accuracy of UTE imaging in skull fracture diagnosis was analysed using receiver operating characteristic (ROC) curve analysis, McNemar’s test and Kappa values. Differences among CT, UTE imaging and anatomical measurement (AM) values for linear fractures (LFs) and depressed fractures (DFs) were compared using one-way ANOVA and a paired-samples t-test. Results UTE imaging clearly demonstrated skull structures and fractures. The accuracy, validity and reliability of UTE MRI were excellent, with no significant differences between expert readings ( P  &gt; 0.05; Kappa, 0.899). The values obtained for 42 LFs and 13 DFs in the ten specimens were not significantly different among CT, UTE MRI and AMs, while those obtained for 55 LFs and ten DFs in 44 patients were not significantly different between CT and UTE MRI ( P  &gt; 0.05). Conclusions UTE MRI sequences are feasible for the evaluation of skull structures and fractures, with no radiation exposure, particularly for paediatric and pregnant patients. Key Points • Despite ionising radiation, CT is standard for skull fracture assessment . • Conventional MRI cannot depict skull structures . • 3D-UTE sequences clearly demonstrate skull structures and fractures . • UTE plus conventional MRI are superior to CT in craniocerebral trauma assessment . • Paediatric and pregnant patients will benefit from this imaging modality .</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-015-3804-2</identifier><identifier>PMID: 25994196</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Aged ; Animals ; Cancer ; Child ; Child, Preschool ; Coma ; Diagnostic Radiology ; Disease Models, Animal ; Drug dosages ; Echo-Planar Imaging - methods ; Feasibility Studies ; Female ; Fractures ; Hospitals ; Humans ; Imaging ; Imaging, Three-Dimensional - methods ; Infant ; Infant, Newborn ; Internal Medicine ; Interventional Radiology ; Magnetic Resonance ; Magnetic resonance imaging ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neuroradiology ; Neurosurgery ; Patients ; Pediatrics ; Radiation ; Radiology ; Reproducibility of Results ; ROC Curve ; Skull Fractures - diagnosis ; Swine ; Swine, Miniature ; Tomography ; Tomography, X-Ray Computed ; Trauma ; Ultrasound ; Young Adult</subject><ispartof>European radiology, 2016-01, Vol.26 (1), p.138-146</ispartof><rights>European Society of Radiology 2015</rights><rights>European Society of Radiology 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c516t-7a0835982c6da206ea845eafe71874857b0dd705d826d254eed1161e05a0bbde3</citedby><cites>FETCH-LOGICAL-c516t-7a0835982c6da206ea845eafe71874857b0dd705d826d254eed1161e05a0bbde3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-015-3804-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-015-3804-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25994196$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wu, Hao</creatorcontrib><creatorcontrib>Zhong, Yu-min</creatorcontrib><creatorcontrib>Nie, Quan-min</creatorcontrib><creatorcontrib>Chen, Wei-bo</creatorcontrib><creatorcontrib>Guo, Lie-mei</creatorcontrib><creatorcontrib>Yang, Xi</creatorcontrib><creatorcontrib>Zhang, Hong</creatorcontrib><creatorcontrib>Lin, Yi</creatorcontrib><creatorcontrib>Xu, Jian-rong</creatorcontrib><creatorcontrib>Dai, Yong-ming</creatorcontrib><creatorcontrib>Zhu, Ming</creatorcontrib><title>Feasibility of three-dimensional ultrashort echo time magnetic resonance imaging at 1.5 T for the diagnosis of skull fractures</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives To investigate the feasibility of ultrashort echo time (UTE) magnetic resonance imaging (MRI) for the diagnosis of skull fractures. Methods The skull fracture models of ten Bama pigs and 364 patients with craniocerebral trauma were subjected to computed tomography (CT), UTE and conventional MRI sequences. The accuracy of UTE imaging in skull fracture diagnosis was analysed using receiver operating characteristic (ROC) curve analysis, McNemar’s test and Kappa values. Differences among CT, UTE imaging and anatomical measurement (AM) values for linear fractures (LFs) and depressed fractures (DFs) were compared using one-way ANOVA and a paired-samples t-test. Results UTE imaging clearly demonstrated skull structures and fractures. The accuracy, validity and reliability of UTE MRI were excellent, with no significant differences between expert readings ( P  &gt; 0.05; Kappa, 0.899). The values obtained for 42 LFs and 13 DFs in the ten specimens were not significantly different among CT, UTE MRI and AMs, while those obtained for 55 LFs and ten DFs in 44 patients were not significantly different between CT and UTE MRI ( P  &gt; 0.05). Conclusions UTE MRI sequences are feasible for the evaluation of skull structures and fractures, with no radiation exposure, particularly for paediatric and pregnant patients. Key Points • Despite ionising radiation, CT is standard for skull fracture assessment . • Conventional MRI cannot depict skull structures . • 3D-UTE sequences clearly demonstrate skull structures and fractures . • UTE plus conventional MRI are superior to CT in craniocerebral trauma assessment . • Paediatric and pregnant patients will benefit from this imaging modality .</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Animals</subject><subject>Cancer</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Coma</subject><subject>Diagnostic Radiology</subject><subject>Disease Models, Animal</subject><subject>Drug dosages</subject><subject>Echo-Planar Imaging - methods</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Fractures</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Imaging</subject><subject>Imaging, Three-Dimensional - methods</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Magnetic Resonance</subject><subject>Magnetic resonance imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine &amp; 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Methods The skull fracture models of ten Bama pigs and 364 patients with craniocerebral trauma were subjected to computed tomography (CT), UTE and conventional MRI sequences. The accuracy of UTE imaging in skull fracture diagnosis was analysed using receiver operating characteristic (ROC) curve analysis, McNemar’s test and Kappa values. Differences among CT, UTE imaging and anatomical measurement (AM) values for linear fractures (LFs) and depressed fractures (DFs) were compared using one-way ANOVA and a paired-samples t-test. Results UTE imaging clearly demonstrated skull structures and fractures. The accuracy, validity and reliability of UTE MRI were excellent, with no significant differences between expert readings ( P  &gt; 0.05; Kappa, 0.899). The values obtained for 42 LFs and 13 DFs in the ten specimens were not significantly different among CT, UTE MRI and AMs, while those obtained for 55 LFs and ten DFs in 44 patients were not significantly different between CT and UTE MRI ( P  &gt; 0.05). Conclusions UTE MRI sequences are feasible for the evaluation of skull structures and fractures, with no radiation exposure, particularly for paediatric and pregnant patients. Key Points • Despite ionising radiation, CT is standard for skull fracture assessment . • Conventional MRI cannot depict skull structures . • 3D-UTE sequences clearly demonstrate skull structures and fractures . • UTE plus conventional MRI are superior to CT in craniocerebral trauma assessment . • Paediatric and pregnant patients will benefit from this imaging modality .</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>25994196</pmid><doi>10.1007/s00330-015-3804-2</doi><tpages>9</tpages></addata></record>
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subjects Adolescent
Adult
Aged
Animals
Cancer
Child
Child, Preschool
Coma
Diagnostic Radiology
Disease Models, Animal
Drug dosages
Echo-Planar Imaging - methods
Feasibility Studies
Female
Fractures
Hospitals
Humans
Imaging
Imaging, Three-Dimensional - methods
Infant
Infant, Newborn
Internal Medicine
Interventional Radiology
Magnetic Resonance
Magnetic resonance imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Neurosurgery
Patients
Pediatrics
Radiation
Radiology
Reproducibility of Results
ROC Curve
Skull Fractures - diagnosis
Swine
Swine, Miniature
Tomography
Tomography, X-Ray Computed
Trauma
Ultrasound
Young Adult
title Feasibility of three-dimensional ultrashort echo time magnetic resonance imaging at 1.5 T for the diagnosis of skull fractures
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