Intratumor stromal proportion predicts aggressive phenotype of gastric signet ring cell carcinomas

Objective The aim of this study was to evaluate the prognostic significance of the intratumor stromal proportion in gastric signet ring cell (SRC) carcinomas. Background Cancer stroma, as exemplified by cancer-associated fibroblasts (CAFs), plays critical roles in cancer proliferation, invasion, and...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2017-07, Vol.20 (4), p.591-601
Hauptverfasser:	Lee, Dakeun, Ham, In-Hye, Son, Sang Yong, Han, Sang-Uk, Kim, Young-Bae, Hur, Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adult Aged Aged, 80 and over Cancer Cancer Research Cancer-Associated Fibroblasts - pathology Carcinoma Carcinoma, Signet Ring Cell - mortality Carcinoma, Signet Ring Cell - pathology Cell migration Disease-Free Survival Female Fibroblasts Gastric cancer Gastroenterology Humans Kaplan-Meier Estimate Male Medicine Medicine & Public Health Mesenchyme Metastases Middle Aged Multivariate analysis Oncology Original Article Phenotype Prognosis Ribonucleic acid RNA Src protein Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stroma Surgical Oncology Survival Tumor Microenvironment Young Adult
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