Clinical and genetic association, radiological findings and response to biological therapy in seven children from Qatar with non‐bacterial osteomyelitis

Aim We aim to report the clinical manifestations, genetic testing results, magnetic resonance imaging (MRI) findings and biologics used in the management of non‐bacterial osteomyelitis in our center. Methods We conducted a retrospective review of medical records. A previously proposed classification...

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Veröffentlicht in:	International journal of rheumatic diseases 2017-09, Vol.20 (9), p.1286-1296
Hauptverfasser:	Moussa, Taha, Bhat, Venkatraman, Kini, Vishwanatha, Fathalla, Basil M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adolescent Age of Onset Anemia Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Arthralgia Arthritis autoinflammatory disorders Bacteria Biological Products - adverse effects Biological Products - therapeutic use Child Child, Preschool Children chronic recurrent multifocal osteomyelitis Cytoskeletal Proteins - genetics DNA Mutational Analysis Familial Mediterranean fever Female Fibula Genetic Predisposition to Disease Genetic screening Humans Infant Infliximab Infliximab - adverse effects Infliximab - therapeutic use Joint diseases Magnetic Resonance Imaging Majeed syndrome Male Medical records Monoclonal antibodies Mutation NMR non‐bacterial osteomyelitis Nuclear magnetic resonance Nuclear Proteins - genetics Osteomyelitis Osteomyelitis - diagnostic imaging Osteomyelitis - drug therapy Osteomyelitis - genetics Osteomyelitis - immunology Patients Phenotype Pyrin - genetics Pyrin protein Qatar Remission Retrospective Studies Siblings Tibia Treatment Outcome Tumor necrosis factor-α
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