Seizure control and cognitive improvement via immunotherapy in late onset epilepsy patients with paraneoplastic versus GAD65 autoantibody-associated limbic encephalitis

Abstract Objective To determine the efficacy of immunotherapy in limbic encephalitis (LE) associated epilepsies with autoantibodies against intracellular antigens in the forms of paraneoplastic autoantibodies versus glutamic acid decarboxylase 65 (GAD)-autoantibodies. Methods Eleven paraneoplastic-a...

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Veröffentlicht in:	Epilepsy & behavior 2016-12, Vol.65, p.18-24
Hauptverfasser:	Hansen, N, Widman, G, Witt, J.-A, Wagner, J, Becker, A.J, Elger, C.E, Helmstaedter, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Autoantibodies - blood Brain - diagnostic imaging Brain - metabolism Case-Control Studies Cognition Disorders - blood Cognition Disorders - immunology Cognition Disorders - therapy Epilepsy Epilepsy - blood Epilepsy - immunology Epilepsy - therapy Female Follow-Up Studies GAD65 autoantibodies Glutamate Decarboxylase - blood Humans Immunotherapy Immunotherapy - methods Limbic encephalitis Limbic Encephalitis - blood Limbic Encephalitis - immunology Limbic Encephalitis - therapy Magnetic Resonance Imaging - methods Male Middle Aged Neurology Paraneoplastic autoantibodies Retrospective Studies Seizures - blood Seizures - immunology Seizures - therapy
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