Clarifying immunoglobulin gene usage in systemic and localized immunoglobulin light-chain amyloidosis by mass spectrometry

The goal of this study was to investigate the frequency of use of light-chain variable region (IGVL) genes among patients with systemic (ALS) and localized (ALL) amyloidosis and to assess for associations between IGVL gene usage and organ tropism. We evaluated clinic charts from 821 AL patients seen...

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Veröffentlicht in:	Blood 2017-01, Vol.129 (3), p.299-306
Hauptverfasser:	Kourelis, Taxiarchis V., Dasari, Surendra, Theis, Jason D., Ramirez-Alvarado, Marina, Kurtin, Paul J., Gertz, Morie A., Zeldenrust, Steven R., Zenka, Roman M., Dogan, Ahmet, Dispenzieri, Angela
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloidosis - complications Amyloidosis - genetics Genes, Immunoglobulin Heart Diseases Humans Immunoglobulin Light Chains - genetics Immunoglobulin Variable Region Kidney Diseases Tandem Mass Spectrometry
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