Increased subcortical oligodendroglia‐like cells in pharmacoresistant focal epilepsy in children correlate with extensive epileptogenic zones

Summary Objective Cortical resections in epilepsy surgery tend to involve multiple lobes in children, compared to adults, partly due to underlying pathology. Oligodendroglia‐like cells (OLCs) have been observed in surgical specimens from children with pharmacoresistant epilepsy. We hypothesize that...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2016-12, Vol.57 (12), p.2031-2038
Hauptverfasser:	Sakuma, Satoru, Halliday, William C., Nomura, Ruka, Baba, Shiro, Sato, Yosuke, Okanari, Kazuo, Nakajima, Midori, Widjaja, Elysa, Boelman, Cyrus, Ochi, Ayako, Snead, O. Carter, Rutka, James T., Drake, James, Miller, Steven, Otsubo, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Brain - diagnostic imaging Brain - pathology Child Child, Preschool Drug Resistant Epilepsy - diagnostic imaging Drug Resistant Epilepsy - pathology Drug Resistant Epilepsy - surgery Electroencephalography Epileptic spasm Female Glial Fibrillary Acidic Protein - metabolism Gray–white matter junction Humans Infant Magnetic Resonance Imaging Male Multiple‐lobe resection Oligodendroglia - pathology Pediatric epilepsy surgery Phosphopyruvate Hydratase - metabolism Statistics as Topic Treatment Outcome White matter
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