In Silico and Wet Lab Studies Reveal the Cholesterol Lowering Efficacy of Lauric Acid, a Medium Chain Fat of Coconut Oil

The coconut oil (CO) contains 91 % of saturated fatty acids in which 72 % are medium chain fatty acids (MCFAs) like lauric, capric and caprylic acids. In contrast to animal fat, coconut oil has no cholesterol. Despite this fact, CO is sidelined among other vegetable oils due to the health hazards at...

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Veröffentlicht in:	Plant foods for human nutrition (Dordrecht) 2016-12, Vol.71 (4), p.410-415
Hauptverfasser:	Lekshmi Sheela, Devi, Nazeem, Puthiyaveetil Abdulla, Narayanankutty, Arunaksharan, Manalil, Jeksy Jos, Raghavamenon, Achuthan C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspirin - pharmacology Atorvastatin Calcium - pharmacology Chemical synthesis Chemistry Chemistry and Materials Science Chemistry/Food Science Cholesterol Cholesterol - blood Coconut Oil Dose-Response Relationship, Drug Ecology Edible oils Esterase Fatty acids Fatty Acids - analysis Food Science Health hazards Health risks Hydroxymethylglutaryl CoA Reductases - metabolism Hypolipidemic activity Hypolipidemic Agents - analysis Hypolipidemic Agents - pharmacokinetics In vivo methods and tests Lauric acid Lauric Acids - analysis Lauric Acids - pharmacology Lipase Lipoprotein lipase Male Models, Animal Molecular docking Molecular Docking Simulation Nutrition Oils & fats Original Paper Phenolic acids Phenols Plant Oils - chemistry Plant Physiology Proteins Rats Rats, Sprague-Dawley Reductase Reductases Reproducibility of Results Sterol Esterase - metabolism Triglycerides - blood Vegetable oils
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