Allogeneic platelet‐rich plasma affects monocyte differentiation to dendritic cells causing an anti‐inflammatory microenvironment, putatively fostering wound healing

Autologous platelet‐rich plasma (PRP) is used clinically to induce repair of different tissues through the release of bioactive molecules. In some patients, the production of efficient autologous PRP is unfeasible due to their compromised health. Allogeneic PRP mismatched for AB0 and Rh antigens was...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2018-01, Vol.12 (1), p.30-43
Hauptverfasser:	Papait, Andrea, Cancedda, Ranieri, Mastrogiacomo, Maddalena, Poggi, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	allogeneic Antigens CD163 antigen CD25 antigen CD4 antigen Colony-stimulating factor Conditioning Cytokines Dendritic cells Differentiation Foxp3 protein Immune response Immune system Inflammation Interferon Interleukin 10 Interleukin 4 Interleukins Leukocyte migration Leukocytes (granulocytic) Lipopolysaccharides Lymphocytes Lymphocytes T macrophages Mesenchyme Monocytes Peripheral blood Phagocytes Platelets platelet‐rich plasma Priming regeneration, wound healing, platelets Regenerative medicine Repair Side effects Stimulation Tissue engineering Tissues Wound healing
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