Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance

Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance

The cortisol awakening response (CAR) holds promise as a clinically important marker of health status. However, CAR research is routinely challenged by its innate complexity, sensitivity to confounds, and methodological inconsistencies. In this unprecedented characterization of CAR in elite military...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Military medicine 2016-11, Vol.181 (11), p.e1600-e1607
Hauptverfasser: Taylor, Marcus K, Hernández, Lisa M, Fuller, Shiloah A, Sargent, Paul, Padilla, Genieleah A, Harris, Erica
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page e1607
container_issue 11
container_start_page e1600
container_title Military medicine
container_volume 181
creator Taylor, Marcus K
Hernández, Lisa M
Fuller, Shiloah A
Sargent, Paul
Padilla, Genieleah A
Harris, Erica
description The cortisol awakening response (CAR) holds promise as a clinically important marker of health status. However, CAR research is routinely challenged by its innate complexity, sensitivity to confounds, and methodological inconsistencies. In this unprecedented characterization of CAR in elite military men (N = 58), we established summary parameters, evaluated sampling stability across two consecutive days, and explored the effect of subject compliance. Average salivary cortisol concentrations increased nearly 60% within 30 minutes of waking, followed by a swift recovery to waking values at 60 minutes. Approximately one in six were classified as negative responders (i.e.,
doi_str_mv 10.7205/MILMED-D-15-00475
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1841133022</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4271989151</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-6fd6b9fc2a8877aaa7bf8ce6a8cb95c034853221fca77a9f897b2156050e68a63</originalsourceid><addsrcrecordid>eNpdkc1v1DAQxS0EotvCH8AFWeLCoQF_xB_hVu1uodKuQBQkbtbEO0Ypib3YCYj_noQtHDg9jeb3nkbzCHnG2SsjmHq9v9ntt5tqU3FVMVYb9YCseCNZpbn88pCsGBO6qplRZ-S8lDvGeN1Y_picCWPrpm7UivxYpzx2JfX06id8w9jFr_QjlmOKBWkX6bbvRqT7bhbIv-ge4xt6Ow3DMnyADAOOmMslvR2hXaAFgTJlHDCOlxTigW5DQD_SFOg6Dce-g-jxCXkUoC_49F4vyOfr7af1u2r3_u3N-mpXeWnEWOlw0G0TvABrjQEA0wbrUYP1baM8k7VVUggePMzrJtjGtIIrzRRDbUHLC_LylHvM6fuEZXRDVzz2PURMU3Hc1pxLyYSY0Rf_oXdpynG-bqH0nCmEmSl-onxOpWQM7pi75RuOM7eU4k6luI3jyv0pZfY8v0-e2gEP_xx_W5C_AYSTiHY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1846605227</pqid></control><display><type>article</type><title>Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Taylor, Marcus K ; Hernández, Lisa M ; Fuller, Shiloah A ; Sargent, Paul ; Padilla, Genieleah A ; Harris, Erica</creator><creatorcontrib>Taylor, Marcus K ; Hernández, Lisa M ; Fuller, Shiloah A ; Sargent, Paul ; Padilla, Genieleah A ; Harris, Erica</creatorcontrib><description>The cortisol awakening response (CAR) holds promise as a clinically important marker of health status. However, CAR research is routinely challenged by its innate complexity, sensitivity to confounds, and methodological inconsistencies. In this unprecedented characterization of CAR in elite military men (N = 58), we established summary parameters, evaluated sampling stability across two consecutive days, and explored the effect of subject compliance. Average salivary cortisol concentrations increased nearly 60% within 30 minutes of waking, followed by a swift recovery to waking values at 60 minutes. Approximately one in six were classified as negative responders (i.e., &lt;0% change from waking to 30-minute postawakening). Three summary parameters of magnitude, as well as three summary parameters of pattern, were computed. Consistent with our hypothesis, summary parameters of magnitude displayed superior stability compared with summary parameters of pattern in the total sample. As expected, compliance with target sampling times was relatively good; average deviations of self-reported morning sampling times in relation to actigraph-derived wake times across both days were within ±5 minutes, and nearly two-thirds of the sample was classified as CAR compliant across both days. Although compliance had equivocal effects on some measures of magnitude, it substantially improved the stability of summary parameters of pattern. The first of its kind, this study established the foundation for a program of CAR research in a profoundly resilient yet chronically stressed population. Building from this, our forthcoming research will evaluate demographic, biobehavioral, and clinical determinants of CAR in this unique population.</description><identifier>ISSN: 0026-4075</identifier><identifier>EISSN: 1930-613X</identifier><identifier>DOI: 10.7205/MILMED-D-15-00475</identifier><identifier>PMID: 27849495</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><ispartof>Military medicine, 2016-11, Vol.181 (11), p.e1600-e1607</ispartof><rights>Reprint &amp; Copyright © 2016 Association of Military Surgeons of the U.S.</rights><rights>Copyright Association of Military Surgeons of the United States Nov/Dec 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-6fd6b9fc2a8877aaa7bf8ce6a8cb95c034853221fca77a9f897b2156050e68a63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27849495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Taylor, Marcus K</creatorcontrib><creatorcontrib>Hernández, Lisa M</creatorcontrib><creatorcontrib>Fuller, Shiloah A</creatorcontrib><creatorcontrib>Sargent, Paul</creatorcontrib><creatorcontrib>Padilla, Genieleah A</creatorcontrib><creatorcontrib>Harris, Erica</creatorcontrib><title>Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance</title><title>Military medicine</title><addtitle>Mil Med</addtitle><description>The cortisol awakening response (CAR) holds promise as a clinically important marker of health status. However, CAR research is routinely challenged by its innate complexity, sensitivity to confounds, and methodological inconsistencies. In this unprecedented characterization of CAR in elite military men (N = 58), we established summary parameters, evaluated sampling stability across two consecutive days, and explored the effect of subject compliance. Average salivary cortisol concentrations increased nearly 60% within 30 minutes of waking, followed by a swift recovery to waking values at 60 minutes. Approximately one in six were classified as negative responders (i.e., &lt;0% change from waking to 30-minute postawakening). Three summary parameters of magnitude, as well as three summary parameters of pattern, were computed. Consistent with our hypothesis, summary parameters of magnitude displayed superior stability compared with summary parameters of pattern in the total sample. As expected, compliance with target sampling times was relatively good; average deviations of self-reported morning sampling times in relation to actigraph-derived wake times across both days were within ±5 minutes, and nearly two-thirds of the sample was classified as CAR compliant across both days. Although compliance had equivocal effects on some measures of magnitude, it substantially improved the stability of summary parameters of pattern. The first of its kind, this study established the foundation for a program of CAR research in a profoundly resilient yet chronically stressed population. Building from this, our forthcoming research will evaluate demographic, biobehavioral, and clinical determinants of CAR in this unique population.</description><issn>0026-4075</issn><issn>1930-613X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkc1v1DAQxS0EotvCH8AFWeLCoQF_xB_hVu1uodKuQBQkbtbEO0Ypib3YCYj_noQtHDg9jeb3nkbzCHnG2SsjmHq9v9ntt5tqU3FVMVYb9YCseCNZpbn88pCsGBO6qplRZ-S8lDvGeN1Y_picCWPrpm7UivxYpzx2JfX06id8w9jFr_QjlmOKBWkX6bbvRqT7bhbIv-ge4xt6Ow3DMnyADAOOmMslvR2hXaAFgTJlHDCOlxTigW5DQD_SFOg6Dce-g-jxCXkUoC_49F4vyOfr7af1u2r3_u3N-mpXeWnEWOlw0G0TvABrjQEA0wbrUYP1baM8k7VVUggePMzrJtjGtIIrzRRDbUHLC_LylHvM6fuEZXRDVzz2PURMU3Hc1pxLyYSY0Rf_oXdpynG-bqH0nCmEmSl-onxOpWQM7pi75RuOM7eU4k6luI3jyv0pZfY8v0-e2gEP_xx_W5C_AYSTiHY</recordid><startdate>201611</startdate><enddate>201611</enddate><creator>Taylor, Marcus K</creator><creator>Hernández, Lisa M</creator><creator>Fuller, Shiloah A</creator><creator>Sargent, Paul</creator><creator>Padilla, Genieleah A</creator><creator>Harris, Erica</creator><general>Oxford University Press</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>4T-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88F</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M1Q</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>201611</creationdate><title>Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance</title><author>Taylor, Marcus K ; Hernández, Lisa M ; Fuller, Shiloah A ; Sargent, Paul ; Padilla, Genieleah A ; Harris, Erica</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-6fd6b9fc2a8877aaa7bf8ce6a8cb95c034853221fca77a9f897b2156050e68a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Taylor, Marcus K</creatorcontrib><creatorcontrib>Hernández, Lisa M</creatorcontrib><creatorcontrib>Fuller, Shiloah A</creatorcontrib><creatorcontrib>Sargent, Paul</creatorcontrib><creatorcontrib>Padilla, Genieleah A</creatorcontrib><creatorcontrib>Harris, Erica</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Military Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Military Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Military medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Taylor, Marcus K</au><au>Hernández, Lisa M</au><au>Fuller, Shiloah A</au><au>Sargent, Paul</au><au>Padilla, Genieleah A</au><au>Harris, Erica</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance</atitle><jtitle>Military medicine</jtitle><addtitle>Mil Med</addtitle><date>2016-11</date><risdate>2016</risdate><volume>181</volume><issue>11</issue><spage>e1600</spage><epage>e1607</epage><pages>e1600-e1607</pages><issn>0026-4075</issn><eissn>1930-613X</eissn><abstract>The cortisol awakening response (CAR) holds promise as a clinically important marker of health status. However, CAR research is routinely challenged by its innate complexity, sensitivity to confounds, and methodological inconsistencies. In this unprecedented characterization of CAR in elite military men (N = 58), we established summary parameters, evaluated sampling stability across two consecutive days, and explored the effect of subject compliance. Average salivary cortisol concentrations increased nearly 60% within 30 minutes of waking, followed by a swift recovery to waking values at 60 minutes. Approximately one in six were classified as negative responders (i.e., &lt;0% change from waking to 30-minute postawakening). Three summary parameters of magnitude, as well as three summary parameters of pattern, were computed. Consistent with our hypothesis, summary parameters of magnitude displayed superior stability compared with summary parameters of pattern in the total sample. As expected, compliance with target sampling times was relatively good; average deviations of self-reported morning sampling times in relation to actigraph-derived wake times across both days were within ±5 minutes, and nearly two-thirds of the sample was classified as CAR compliant across both days. Although compliance had equivocal effects on some measures of magnitude, it substantially improved the stability of summary parameters of pattern. The first of its kind, this study established the foundation for a program of CAR research in a profoundly resilient yet chronically stressed population. Building from this, our forthcoming research will evaluate demographic, biobehavioral, and clinical determinants of CAR in this unique population.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>27849495</pmid><doi>10.7205/MILMED-D-15-00475</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0026-4075
ispartof Military medicine, 2016-11, Vol.181 (11), p.e1600-e1607
issn 0026-4075
1930-613X
language eng
recordid cdi_proquest_miscellaneous_1841133022
source Oxford University Press Journals All Titles (1996-Current); Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
title Cortisol Awakening Response in Elite Military Men: Summary Parameters, Stability Measurement, and Effect of Compliance
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T09%3A00%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cortisol%20Awakening%20Response%20in%20Elite%20Military%20Men:%20Summary%20Parameters,%20Stability%20Measurement,%20and%20Effect%20of%20Compliance&rft.jtitle=Military%20medicine&rft.au=Taylor,%20Marcus%20K&rft.date=2016-11&rft.volume=181&rft.issue=11&rft.spage=e1600&rft.epage=e1607&rft.pages=e1600-e1607&rft.issn=0026-4075&rft.eissn=1930-613X&rft_id=info:doi/10.7205/MILMED-D-15-00475&rft_dat=%3Cproquest_cross%3E4271989151%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1846605227&rft_id=info:pmid/27849495&rfr_iscdi=true