Associations between common polymorphisms in TP53 and p21WAF1/Cip1 and phenotypic features of breast cancer

The tumour suppressor gene TP53 and its downstream effector p21 are thought to play major roles in the development of breast cancer. We investigated three common sequence variants in TP53 and p21 for possible associations with the risk of breast cancer and with various phenotypic features of this di...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Carcinogenesis (New York) 2002-02, Vol.23 (2), p.311-315
Hauptverfasser:	Powell, Brenda L., van Staveren, Iris L., Roosken, Paul, Grieu, Fabienne, Berns, Els M.J.J., Iacopetta, Barry
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Biological and medical sciences Breast Neoplasms - genetics Cyclin-Dependent Kinase Inhibitor p21 Cyclins - genetics F-SSCP Female fluorescent single strand conformation polymorphism Genes, p53 - genetics Genotype Gynecology. Andrology. Obstetrics Humans Introns Mammary gland diseases Medical sciences Middle Aged Molecular Sequence Data Phenotype Polymorphism, Genetic Polymorphism, Single Nucleotide Polymorphism, Single-Stranded Conformational Progesterone - metabolism Risk Factors Signal Transduction Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!