Cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats

Boesenbergia rotunda (L.) Mansf. had been traditionally used as herbs to treat pain and rheumatism. Cardamonin (2′,4′-dihydroxy-6′-methoxychalcone) is a compound isolated from Boesenbergia rotunda (L.) Mansf.. Previous study had shown the potential of cardamonin in inhibiting the release of pro-infl...

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Veröffentlicht in:	European journal of pharmacology 2017-01, Vol.794, p.127-134
Hauptverfasser:	Voon, Fui-Ling, Sulaiman, Mohd Roslan, Akhtar, Muhammad Nadeem, Idris, Mohamad Fauzi, Akira, Ahmad, Perimal, Enoch Kumar, Israf, Daud Ahmad, Ming-Tatt, Lee
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory Antinociceptive Arthritis, Experimental - blood Arthritis, Experimental - chemically induced Arthritis, Experimental - drug therapy Arthritis, Experimental - pathology Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - chemically induced Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - pathology Boesenbergia rotunda (L.) Mansf Cardamonin Chalcones - isolation & purification Chalcones - pharmacology Chalcones - therapeutic use Chalcones - toxicity Edema - chemically induced Edema - drug therapy Edema - pathology Freund's Adjuvant - pharmacology Hyperalgesia - chemically induced Hyperalgesia - drug therapy Interleukin-1beta - blood Interleukin-6 - blood Male Rats Rats, Sprague-Dawley Rheumatoid arthritis Tumor Necrosis Factor-alpha - blood Zingiberaceae - chemistry
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