Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) has been subclassified into 3 molecular subtypes: classical, quasi-mesenchymal, and exocrine-like. These subtypes exhibit differences in patient survival and drug resistance to conventional therapies. The aim of the current study is to identify novel subtype-s...

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Veröffentlicht in:	Pancreas 2017-03, Vol.46 (3), p.311-322
Hauptverfasser:	Kuhlmann, Laura, Nadler, Wiebke M, Kerner, Alexander, Hanke, Sabrina A, Noll, Elisa M, Eisen, Christian, Espinet, Elisa, Vogel, Vanessa, Trumpp, Andreas, Sprick, Martin R, Roesli, Christoph P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers, Tumor - metabolism Cadherins - metabolism Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - metabolism Galectin 4 - metabolism Humans Lipocalin-2 - metabolism Mice Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - metabolism Proteome - metabolism Proteomics - methods Reproducibility of Results Sensitivity and Specificity Transplantation, Heterologous
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