Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification
Abstract Objective Anxiety disorders contribute substantially to the overall public health burden. Anxiety sensitivity (AS), a fear of anxiety-related sensations, is one of the few known malleable risk factors for anxiety pathology. Previous AS reduction treatments have primarily utilized “top-down”...
Gespeichert in:
| Veröffentlicht in: | Journal of psychiatric research 2017-02, Vol.85, p.75-82 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 82 |
|---|---|
| container_issue | |
| container_start_page | 75 |
| container_title | Journal of psychiatric research |
| container_volume | 85 |
| creator | Capron, Daniel W Norr, Aaron M Allan, Nicholas P Schmidt, Norman B |
| description | Abstract Objective Anxiety disorders contribute substantially to the overall public health burden. Anxiety sensitivity (AS), a fear of anxiety-related sensations, is one of the few known malleable risk factors for anxiety pathology. Previous AS reduction treatments have primarily utilized “top-down” (e.g., psychoeducation) interventions. The goal of the current study was to evaluate the effect of adding a “bottom-up” (interpretation bias modification; CBM-I) intervention to an AS psychoeducation intervention. Design Single-site randomized controlled trial. Participants completed either a 1) Psychoeducation + active CBM-I or 2) Psychoeducation + control CBM-I intervention. Change in AS was assessed post-intervention and at a one-month follow-up. Participants Individuals with elevated levels of AS. Intervention Single-session computer-delivered intervention for AS. Results Accounting for baseline ASI-3 scores, post-intervention ASI-3 scores were significantly lower in the combined condition than in the psychoeducation + control CBM-I condition (β = 0.24, p |
| doi_str_mv | 10.1016/j.jpsychires.2016.11.003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1839121550</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022395616306100</els_id><sourcerecordid>1839121550</sourcerecordid><originalsourceid>FETCH-LOGICAL-c429t-4301bc02d1bef65f21e4e13690b7d835b37c99b5b9f4128c2ba47b33653869f73</originalsourceid><addsrcrecordid>eNqNks9u1DAQxiMEokvhFZCPXLL12PnLAQlWUJAqgQScrdgZUy-JHWxny3Lqg8Cd5-qT4OwWkDhxsvTpm9945pssI0DXQKE62663U9irS-MxrFlS1gBrSvmdbAVN3ebA6_ZutqKUsZy3ZXWSPQhhSymtGRT3sxNWN7yuKrrKfm7cKI3Fntxcf49uynt3ZW-uf5DOHiTpYnRjPk-LZmxEv0MbjbNEO59MXw3GPQlog4lmZ-L-KXlnBheJTwA3mm-JHL3pBhIxRGM_kXiJpOv7xY4EtUYVidNH9uQxdge6NF0go-uNNuqgPMzu6W4I-Oj2Pc0-vnr5YfM6v3h7_mbz_CJXBWtjXnAKUlHWg0RdlZoBFgi8aqms-4aXkteqbWUpW10AaxSTXVFLzquSN1Wra36aPTlyJ---zOnPYjRB4TB0Ft0cBDS8BQZlSZO1OVqVdyF41GLyZuz8XgAVS05iK_7mJJacBIBIOaXSx7ddZjli_6fwdzDJ8OJowDTrzqAXQRm0CvvEUlH0zvxPl2f_QNRgbFro8Bn3GLZu9jbtUoAITFDxfrmX5Vyg4rSCRPgFnbbGgQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1839121550</pqid></control><display><type>article</type><title>Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Capron, Daniel W ; Norr, Aaron M ; Allan, Nicholas P ; Schmidt, Norman B</creator><creatorcontrib>Capron, Daniel W ; Norr, Aaron M ; Allan, Nicholas P ; Schmidt, Norman B</creatorcontrib><description>Abstract Objective Anxiety disorders contribute substantially to the overall public health burden. Anxiety sensitivity (AS), a fear of anxiety-related sensations, is one of the few known malleable risk factors for anxiety pathology. Previous AS reduction treatments have primarily utilized “top-down” (e.g., psychoeducation) interventions. The goal of the current study was to evaluate the effect of adding a “bottom-up” (interpretation bias modification; CBM-I) intervention to an AS psychoeducation intervention. Design Single-site randomized controlled trial. Participants completed either a 1) Psychoeducation + active CBM-I or 2) Psychoeducation + control CBM-I intervention. Change in AS was assessed post-intervention and at a one-month follow-up. Participants Individuals with elevated levels of AS. Intervention Single-session computer-delivered intervention for AS. Results Accounting for baseline ASI-3 scores, post-intervention ASI-3 scores were significantly lower in the combined condition than in the psychoeducation + control CBM-I condition (β = 0.24, p < 0.05; d = 0.99). The active CBM-I plus psychoeducation AS intervention was successful in reducing overall AS (59% post-intervention; p < .05, Cohen's d = 0.99) and these reductions were maintained through one-month post-intervention (52%; p < .05, Cohen's d = 1.18). Participants in the active condition reported significantly lower rates of panic responding to a vital-capacity CO2 challenge (OR = 6.34, 95% CI = 1.07–37.66). Lastly, change in interpretation bias significantly mediated the relationship between treatment condition and post-treatment AS reductions. Conclusions The current intervention was efficacious in terms of immediate and one-month AS reductions. Given its brevity, low-cost, low-stigma and portability, this intervention could lead to reducing the burden of anxiety disorders.</description><identifier>ISSN: 0022-3956</identifier><identifier>EISSN: 1879-1379</identifier><identifier>DOI: 10.1016/j.jpsychires.2016.11.003</identifier><identifier>PMID: 27837660</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Anxiety - physiopathology ; Anxiety - therapy ; Anxiety Disorders - therapy ; Carbon Monoxide ; Cognitive Behavioral Therapy - methods ; Female ; Follow-Up Studies ; Humans ; Male ; Panic - physiology ; Pilot Projects ; Psychiatric Status Rating Scales ; Psychiatry ; Self Report ; Therapy, Computer-Assisted - methods ; Treatment Outcome ; Vital Capacity ; Young Adult</subject><ispartof>Journal of psychiatric research, 2017-02, Vol.85, p.75-82</ispartof><rights>2016 Elsevier Ltd</rights><rights>Copyright © 2016 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c429t-4301bc02d1bef65f21e4e13690b7d835b37c99b5b9f4128c2ba47b33653869f73</citedby><cites>FETCH-LOGICAL-c429t-4301bc02d1bef65f21e4e13690b7d835b37c99b5b9f4128c2ba47b33653869f73</cites><orcidid>0000-0002-5066-4644</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022395616306100$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27837660$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Capron, Daniel W</creatorcontrib><creatorcontrib>Norr, Aaron M</creatorcontrib><creatorcontrib>Allan, Nicholas P</creatorcontrib><creatorcontrib>Schmidt, Norman B</creatorcontrib><title>Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification</title><title>Journal of psychiatric research</title><addtitle>J Psychiatr Res</addtitle><description>Abstract Objective Anxiety disorders contribute substantially to the overall public health burden. Anxiety sensitivity (AS), a fear of anxiety-related sensations, is one of the few known malleable risk factors for anxiety pathology. Previous AS reduction treatments have primarily utilized “top-down” (e.g., psychoeducation) interventions. The goal of the current study was to evaluate the effect of adding a “bottom-up” (interpretation bias modification; CBM-I) intervention to an AS psychoeducation intervention. Design Single-site randomized controlled trial. Participants completed either a 1) Psychoeducation + active CBM-I or 2) Psychoeducation + control CBM-I intervention. Change in AS was assessed post-intervention and at a one-month follow-up. Participants Individuals with elevated levels of AS. Intervention Single-session computer-delivered intervention for AS. Results Accounting for baseline ASI-3 scores, post-intervention ASI-3 scores were significantly lower in the combined condition than in the psychoeducation + control CBM-I condition (β = 0.24, p < 0.05; d = 0.99). The active CBM-I plus psychoeducation AS intervention was successful in reducing overall AS (59% post-intervention; p < .05, Cohen's d = 0.99) and these reductions were maintained through one-month post-intervention (52%; p < .05, Cohen's d = 1.18). Participants in the active condition reported significantly lower rates of panic responding to a vital-capacity CO2 challenge (OR = 6.34, 95% CI = 1.07–37.66). Lastly, change in interpretation bias significantly mediated the relationship between treatment condition and post-treatment AS reductions. Conclusions The current intervention was efficacious in terms of immediate and one-month AS reductions. Given its brevity, low-cost, low-stigma and portability, this intervention could lead to reducing the burden of anxiety disorders.</description><subject>Adolescent</subject><subject>Anxiety - physiopathology</subject><subject>Anxiety - therapy</subject><subject>Anxiety Disorders - therapy</subject><subject>Carbon Monoxide</subject><subject>Cognitive Behavioral Therapy - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Panic - physiology</subject><subject>Pilot Projects</subject><subject>Psychiatric Status Rating Scales</subject><subject>Psychiatry</subject><subject>Self Report</subject><subject>Therapy, Computer-Assisted - methods</subject><subject>Treatment Outcome</subject><subject>Vital Capacity</subject><subject>Young Adult</subject><issn>0022-3956</issn><issn>1879-1379</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNks9u1DAQxiMEokvhFZCPXLL12PnLAQlWUJAqgQScrdgZUy-JHWxny3Lqg8Cd5-qT4OwWkDhxsvTpm9945pssI0DXQKE62663U9irS-MxrFlS1gBrSvmdbAVN3ebA6_ZutqKUsZy3ZXWSPQhhSymtGRT3sxNWN7yuKrrKfm7cKI3Fntxcf49uynt3ZW-uf5DOHiTpYnRjPk-LZmxEv0MbjbNEO59MXw3GPQlog4lmZ-L-KXlnBheJTwA3mm-JHL3pBhIxRGM_kXiJpOv7xY4EtUYVidNH9uQxdge6NF0go-uNNuqgPMzu6W4I-Oj2Pc0-vnr5YfM6v3h7_mbz_CJXBWtjXnAKUlHWg0RdlZoBFgi8aqms-4aXkteqbWUpW10AaxSTXVFLzquSN1Wra36aPTlyJ---zOnPYjRB4TB0Ft0cBDS8BQZlSZO1OVqVdyF41GLyZuz8XgAVS05iK_7mJJacBIBIOaXSx7ddZjli_6fwdzDJ8OJowDTrzqAXQRm0CvvEUlH0zvxPl2f_QNRgbFro8Bn3GLZu9jbtUoAITFDxfrmX5Vyg4rSCRPgFnbbGgQ</recordid><startdate>20170201</startdate><enddate>20170201</enddate><creator>Capron, Daniel W</creator><creator>Norr, Aaron M</creator><creator>Allan, Nicholas P</creator><creator>Schmidt, Norman B</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5066-4644</orcidid></search><sort><creationdate>20170201</creationdate><title>Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification</title><author>Capron, Daniel W ; Norr, Aaron M ; Allan, Nicholas P ; Schmidt, Norman B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c429t-4301bc02d1bef65f21e4e13690b7d835b37c99b5b9f4128c2ba47b33653869f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Anxiety - physiopathology</topic><topic>Anxiety - therapy</topic><topic>Anxiety Disorders - therapy</topic><topic>Carbon Monoxide</topic><topic>Cognitive Behavioral Therapy - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Panic - physiology</topic><topic>Pilot Projects</topic><topic>Psychiatric Status Rating Scales</topic><topic>Psychiatry</topic><topic>Self Report</topic><topic>Therapy, Computer-Assisted - methods</topic><topic>Treatment Outcome</topic><topic>Vital Capacity</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Capron, Daniel W</creatorcontrib><creatorcontrib>Norr, Aaron M</creatorcontrib><creatorcontrib>Allan, Nicholas P</creatorcontrib><creatorcontrib>Schmidt, Norman B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of psychiatric research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Capron, Daniel W</au><au>Norr, Aaron M</au><au>Allan, Nicholas P</au><au>Schmidt, Norman B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification</atitle><jtitle>Journal of psychiatric research</jtitle><addtitle>J Psychiatr Res</addtitle><date>2017-02-01</date><risdate>2017</risdate><volume>85</volume><spage>75</spage><epage>82</epage><pages>75-82</pages><issn>0022-3956</issn><eissn>1879-1379</eissn><abstract>Abstract Objective Anxiety disorders contribute substantially to the overall public health burden. Anxiety sensitivity (AS), a fear of anxiety-related sensations, is one of the few known malleable risk factors for anxiety pathology. Previous AS reduction treatments have primarily utilized “top-down” (e.g., psychoeducation) interventions. The goal of the current study was to evaluate the effect of adding a “bottom-up” (interpretation bias modification; CBM-I) intervention to an AS psychoeducation intervention. Design Single-site randomized controlled trial. Participants completed either a 1) Psychoeducation + active CBM-I or 2) Psychoeducation + control CBM-I intervention. Change in AS was assessed post-intervention and at a one-month follow-up. Participants Individuals with elevated levels of AS. Intervention Single-session computer-delivered intervention for AS. Results Accounting for baseline ASI-3 scores, post-intervention ASI-3 scores were significantly lower in the combined condition than in the psychoeducation + control CBM-I condition (β = 0.24, p < 0.05; d = 0.99). The active CBM-I plus psychoeducation AS intervention was successful in reducing overall AS (59% post-intervention; p < .05, Cohen's d = 0.99) and these reductions were maintained through one-month post-intervention (52%; p < .05, Cohen's d = 1.18). Participants in the active condition reported significantly lower rates of panic responding to a vital-capacity CO2 challenge (OR = 6.34, 95% CI = 1.07–37.66). Lastly, change in interpretation bias significantly mediated the relationship between treatment condition and post-treatment AS reductions. Conclusions The current intervention was efficacious in terms of immediate and one-month AS reductions. Given its brevity, low-cost, low-stigma and portability, this intervention could lead to reducing the burden of anxiety disorders.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>27837660</pmid><doi>10.1016/j.jpsychires.2016.11.003</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-5066-4644</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3956 |
| ispartof | Journal of psychiatric research, 2017-02, Vol.85, p.75-82 |
| issn | 0022-3956 1879-1379 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1839121550 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adolescent Anxiety - physiopathology Anxiety - therapy Anxiety Disorders - therapy Carbon Monoxide Cognitive Behavioral Therapy - methods Female Follow-Up Studies Humans Male Panic - physiology Pilot Projects Psychiatric Status Rating Scales Psychiatry Self Report Therapy, Computer-Assisted - methods Treatment Outcome Vital Capacity Young Adult |
| title | Combined “top-down” and “bottom-up” intervention for anxiety sensitivity: Pilot randomized trial testing the additive effect of interpretation bias modification |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T16%3A05%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Combined%20%E2%80%9Ctop-down%E2%80%9D%20and%20%E2%80%9Cbottom-up%E2%80%9D%20intervention%20for%20anxiety%20sensitivity:%20Pilot%20randomized%20trial%20testing%20the%20additive%20effect%20of%20interpretation%20bias%20modification&rft.jtitle=Journal%20of%20psychiatric%20research&rft.au=Capron,%20Daniel%20W&rft.date=2017-02-01&rft.volume=85&rft.spage=75&rft.epage=82&rft.pages=75-82&rft.issn=0022-3956&rft.eissn=1879-1379&rft_id=info:doi/10.1016/j.jpsychires.2016.11.003&rft_dat=%3Cproquest_cross%3E1839121550%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1839121550&rft_id=info:pmid/27837660&rft_els_id=S0022395616306100&rfr_iscdi=true |